Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

Jansen, Willemijn J; Visser, Pieter Jelle; Amyloid Biomarker Study Group

doi:10.1001/jamapsychiatry.2017.3391

Scientific article

English

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

ContributorsJansen, Willemijn J; Visser, Pieter Jelle; Amyloid Biomarker Study Group

CollaboratorsFrisoni, Giovanni; Popp, Julius

Published inJAMA Psychiatry, vol. 75, no. 1, p. 84-95

Publication date2018

Abstract

Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD). Understanding the association between amyloid aggregation and cognitive manifestation in persons without dementia is important for a better understanding of the course of AD and for the design of prevention trials.

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de psychiatrie

Research groups

Citation (ISO format)

JANSEN, Willemijn J, VISSER, Pieter Jelle. Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia. In: JAMA Psychiatry, 2018, vol. 75, n° 1, p. 84–95. doi: 10.1001/jamapsychiatry.2017.3391

Article (Published version)

Identifiers

PID : unige:104876
DOI : 10.1001/jamapsychiatry.2017.3391
PMID : 29188296

Journal ISSN2168-622X

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349downloads

Creation05/25/2018 2:59:00 PM

First validation05/25/2018 2:59:00 PM

Update time03/15/2023 8:16:59 AM

Status update03/15/2023 8:16:58 AM

Last indexation10/31/2024 10:21:48 AM

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Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia

Cerebral amyloid-β aggregation is an early event in Alzheimer disease (AD). Understanding the association between amyloid aggregation and cognitive manifestation in persons without dementia is important for a better understanding of the course of AD and for the design of prevention trials.

Technical informations