Cortical Dysconnectivity Measured by Structural Covariance Is Associated With the Presence of Psychotic Symptoms in 22q11.2 Deletion Syndrome

Sandini, Corrado; Scariati Jaussi, Elisa; Padula, Maria; Schneider, Maude; Schaer, Marie; Van De Ville, Dimitri; Eliez, Stéphan

doi:10.1016/j.bpsc.2017.04.008

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Title		Cortical Dysconnectivity Measured by Structural Covariance Is Associated With the Presence of Psychotic Symptoms in 22q11.2 Deletion Syndrome
Authors		Sandini, Corrado Scariati Jaussi, Elisa Padula, Maria Schneider, Maude Schaer, Marie Van De Ville, Dimitri Eliez, Stéphan
Published in		Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2018, vol. 3, no. 5, p. 433-442
Abstract		22q11.2 deletion syndrome (22q11DS) is the third-largest known genetic risk factor for the development of psychosis. Dysconnectivity has consistently been implicated in the physiopathology of psychosis. Structural covariance of cortical morphology is a method of exploring connectivity among brain regions that to date has not been employed in 22q11DS.
Identifiers		DOI: 10.1016/j.bpsc.2017.04.008 PMID: 29735153
Full text		Article (Published version) (741 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de psychiatrie Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale
Research groups		Laboratoire d'imagerie et de psychopathologie développementale (693) Traitement d'images médicales (893)
Citation (ISO format)		SANDINI, Corrado et al. Cortical Dysconnectivity Measured by Structural Covariance Is Associated With the Presence of Psychotic Symptoms in 22q11.2 Deletion Syndrome. In: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 2018, vol. 3, n° 5, p. 433-442. doi: 10.1016/j.bpsc.2017.04.008 https://archive-ouverte.unige.ch/unige:104870