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Scientific article
English

Cell-specific resetting of mouse islet cellular clocks by glucagon, glucagon-like peptide 1 and somatostatin

Published inActa Physiologica, vol. 222, no. 4, e13021
Publication date2018
Abstract

Molecular clocks, operative in pancreatic islet cells, represent an intrinsic mechanism regulating intracellular metabolism and hormone secretion. Glucagon, somatostatin and glucagon-like peptide 1 (GLP-1) are essential coordinators of islet physiology. Here, we assess the synchronizing capacity of glucagon, somatostatin and GLP-1 on pancreatic α- and β-cell circadian clocks.

Keywords
  • circadian bioluminescence
  • circadian oscillator
  • glucagon
  • glucagon-like peptide 1
  • somatostatin
  • α- and β-islet cells
Citation (ISO format)
PETRENKO, Volodymyr, DIBNER, Charna. Cell-specific resetting of mouse islet cellular clocks by glucagon, glucagon-like peptide 1 and somatostatin. In: Acta Physiologica, 2018, vol. 222, n° 4, p. e13021. doi: 10.1111/apha.13021
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Article (Published version)
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Identifiers
ISSN of the journal1748-1708
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Creation04/10/2018 2:39:00 PM
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