mRNA export: RNP remodeling by DEAD-box proteins

Linder, Patrick

doi:10.1016/j.cub.2008.02.027

Scientific article

English

mRNA export: RNP remodeling by DEAD-box proteins

ContributorsLinder, Patrick

Published inCurrent biology, vol. 18, no. 7, p. R297-299

Publication date2008

Abstract

The DEAD-box protein Dbp5 was thought to remodel ribonucleoproteins and displace proteins from these complexes in an ATP-dependent fashion to allow for mRNA export from the nucleus. A recent study on Dbp5 shows, however, that its ADP-bound form may also perform an important function in displacing export factors from mRNA.

Keywords

Adenosine Diphosphate/metabolism
Cell Nucleus/metabolism
DEAD-box RNA Helicases/metabolism
RNA, Messenger/metabolism
Ribonucleoproteins/metabolism

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de microbiologie et médecine moléculaire

Research groups

Acquisition et expression de facteurs de virulence chez Staphylococcus aureus (86)

Citation (ISO format)

LINDER, Patrick. mRNA export: RNP remodeling by DEAD-box proteins. In: Current biology, 2008, vol. 18, n° 7, p. R297–299. doi: 10.1016/j.cub.2008.02.027

Article (Accepted version)

Identifiers

PID : unige:1042
DOI : 10.1016/j.cub.2008.02.027
PMID : 18397738

Journal ISSN0960-9822

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mRNA export: RNP remodeling by DEAD-box proteins

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