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Defining outcomes for beta cell replacement therapy: a work in progress

Piemonti, Lorenzo
de Koning, Eelco J P
Odorico, Jon S
Markmann, James F
Stock, Peter G
Rickels, Michael R
Published in Diabetologia. 2018
Abstract Defined outcomes for beta cell replacement therapy in the treatment of diabetes are critically needed. Progress towards the clinical acceptance of pancreas and islet transplantation has been hampered by the lack of clear definitions of functional and efficacy outcomes, as well as a lack of consistently applied glycaemic control metrics, together with poor alignment with the field of artificial insulin delivery/artificial pancreas development. To address this problem, the International Pancreas & Islet Transplant Association (IPITA) collaborated with the European Pancreas and Islet Transplant Association (EPITA) to develop a consensus for a joint statement on the definition of function and failure of beta cell replacement therapies, which is summarised in this commentary.
Keywords Islet transplantationOutcomesPancreas transplantation
PMID: 29511779
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Research group La transplantation d'îlots de Langerhans (623)
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PIEMONTI, Lorenzo et al. Defining outcomes for beta cell replacement therapy: a work in progress. In: Diabetologia, 2018. doi: 10.1007/s00125-018-4588-0 https://archive-ouverte.unige.ch/unige:103840

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Deposited on : 2018-04-24

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