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Assessing adherence to multiple medications and in daily life among patients with multimorbidity

Inauen, Jennifer
Bierbauer, Walter
Lüscher, Janina
König, Claudia
Tobias, Robert
Zimmerli, Lukas
Holzer, Barbara M.
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Published in Psychology and Health. 2017, vol. 32, no. 10, p. 1233-1248
Abstract OBJECTIVE: Chronic conditions often require multiple medication intake. However, past research has focused on assessing overall adherence or adherence to a single index medication only. This study explored adherence measures for multiple medication intake, and in daily life, among patients with multiple chronic conditions (i.e. multimorbidity). DESIGN: Eighty-four patients with multimorbidity and multiple-medication regimens completed three monthly panel questionnaires. A randomly assigned subsample additionally completed a 30-day daily diary. MAIN OUTCOME MEASURE: The Non-Adherence Report; a brief self-report measure of adherence to each prescribed medication (NAR-M), and in daily life. We further assessed the Medication Adherence Report Scale (MARS), and a subsample of participants were randomised to electronic adherence monitoring. RESULTS: The NAR-M indicated M = 94.7% adherence at Time 1 (SD = 9.3%). The NAR-M was significantly correlated with the MARS (rt1 = .52, rt2 = .57, and rt3 = .65; p < .001), and in tendency with electronically assessed adherence (rt2 = .45, rt3 = .46, p < .10). Variance components analysis indicated that between-person differences accounted for 10.2% of the variance in NAR-M adherence rates, whereas 22.9% were attributable to medication by person interactions. CONCLUSION: This study highlights the importance and feasibility of studying adherence to multiple medications differentially, and in daily life. Future studies may use these measures to investigate within-person and between-medication differences in adherence.
Keywords Electronic medication adherenceMultimorbidityMultiple chronic conditionsMultiple medicationsPolypharmacySelf-report
PMID: 28043163
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Research group Cognitive Aging Lab (CAL)
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INAUEN, Jennifer et al. Assessing adherence to multiple medications and in daily life among patients with multimorbidity. In: Psychology and Health, 2017, vol. 32, n° 10, p. 1233-1248. doi: 10.1080/08870446.2016.1275632 https://archive-ouverte.unige.ch/unige:103501

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Deposited on : 2018-04-12

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