Synaptic plasticity and dynamic modulation of the postsynaptic membrane

Luescher, Christian; Nicoll, R. A.; Malenka, R. C.; Muller, Dominique

doi:10.1038/75714

Scientific article

English

Synaptic plasticity and dynamic modulation of the postsynaptic membrane

ContributorsLuescher, Christian; Nicoll, R. A.; Malenka, R. C.; Muller, Dominique

Published inNature neuroscience, vol. 3, no. 6, p. 545-550

Publication date2000

Abstract

The biochemical composition of the postsynaptic membrane and the structure of dendritic spines may be rapidly modulated by synaptic activity. Here we review these findings, discuss their implications for long-term potentiation (LTP) and long-term depression (LTD) and propose a model of sequentially occurring expression mechanisms.

Keywords

Animals
Cell Size
Dendrites/ metabolism
Long-Term Potentiation/ physiology
Models, Neurological
Nerve Tissue Proteins/metabolism
Neural Inhibition/physiology
Neuronal Plasticity/ physiology
Pseudopodia/metabolism
Receptors, AMPA/metabolism
Signal Transduction/physiology
Synapses/ metabolism
Synaptic Membranes/ metabolism

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de neurosciences fondamentales

Citation (ISO format)

LUESCHER, Christian et al. Synaptic plasticity and dynamic modulation of the postsynaptic membrane. In: Nature neuroscience, 2000, vol. 3, n° 6, p. 545–550. doi: 10.1038/75714

Article

Identifiers

PID : unige:10347
DOI : 10.1038/75714
PMID : 10816309

Additional URL for this publicationhttp://www.nature.com/neuro/journal/v3/n6/full/nn0600_545.html

Journal ISSN1097-6256

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Synaptic plasticity and dynamic modulation of the postsynaptic membrane

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