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Scientific article
English

Synaptic plasticity and dynamic modulation of the postsynaptic membrane

Contributors

Luescher, Christian; Nicoll, R. A.; Malenka, R. C.; Muller, Dominique

Published in

Nature neuroscience, vol. 3, no. 6, p. 545-550

Publication date

2000

Abstract

The biochemical composition of the postsynaptic membrane and the structure of dendritic spines may be rapidly modulated by synaptic activity. Here we review these findings, discuss their implications for long-term potentiation (LTP) and long-term depression (LTD) and propose a model of sequentially occurring expression mechanisms.

Keywords

  • Animals
  • Cell Size
  • Dendrites/ metabolism
  • Long-Term Potentiation/ physiology
  • Models, Neurological
  • Nerve Tissue Proteins/metabolism
  • Neural Inhibition/physiology
  • Neuronal Plasticity/ physiology
  • Pseudopodia/metabolism
  • Receptors, AMPA/metabolism
  • Signal Transduction/physiology
  • Synapses/ metabolism
  • Synaptic Membranes/ metabolism

UNIGE affiliation entities

Citation (ISO format)

LUESCHER, Christian et al. Synaptic plasticity and dynamic modulation of the postsynaptic membrane. In: Nature neuroscience, 2000, vol. 3, n° 6, p. 545–550. doi: 10.1038/75714

Main files (1)

Article

Identifiers

Additional URL for this publication

http://www.nature.com/neuro/journal/v3/n6/full/nn0600_545.html

Journal ISSN

1097-6256
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Technical informations

Creation

06/08/2010 13:47:07

First validation

06/08/2010 13:47:07

Update

14/10/2025 05:54:21

Status update

14/03/2023 15:58:55

Last indexation

02/11/2026 16:36:48
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