UNIGE document Privat-docent Thesis
previous document  unige:103240  next document
add to browser collection
Title

Somatostatin receptor imaging for the diagnosis and management of gastro-entero-pancreatic neuroendocrine tumors

Author
Defense Thèse de privat-docent : Univ. Genève, 2017
Abstract This is a review of my work focusing on molecular diagnostic markers, as well as the staging and surgical management of gastro-entero-pancreatic neuroendocrine tumors (GEP-NETs). We prospectively studied the clinical utility of 68Ga-DOTATATE imaging in the detection of unknown primary tumors and metastatic disease in patients with suspected or known GEP-NETs, and compared it to that of the current FDA-approved imaging modalities such as 111In- pentetreotide single-photon emission computed tomography (SPECT/CT), computed tomography (CT), and/or magnetic resonance imaging (MRI). We found that 68Ga-DOTATATE PET/CT imaging was the most sensitive in the staging and detection of unknown primary GEP-NETs. These findings have opened new avenues for the diagnosis and treatment of GEP-NETs, as well as access to precision surgery, which combined with imaging and tumor genomics, represents the future in terms of the application of personalized cancer management.
Keywords Gastro-entero-pancreatic neuroendocrine tumorsSomatostatin receptor imagingStagingRadio-guided surgery
Identifiers
Full text
Thesis (8.4 MB) - document accessible for UNIGE members only Limited access to UNIGE
Structures
Citation
(ISO format)
SADOWSKI VEUTHEY, Mercedes Samira Doris. Somatostatin receptor imaging for the diagnosis and management of gastro-entero-pancreatic neuroendocrine tumors. Université de Genève. Thèse de privat-docent, 2017. https://archive-ouverte.unige.ch/unige:103240

12 hits

0 download

Update

Deposited on : 2018-03-28

Export document
Format :
Citation style :