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Allergologie et immunologie clinique

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Published in Revue médicale suisse. 2018, vol. 14, no. 588-589, p. 15-18
Abstract Hereditary angioedema (HA) is a disabling and potentially fatal condition. The management of HA includes treatment of acute attacks, short-term prophylaxis to prevent an attack, and long-term prophylaxis to minimize the frequency and severity of recurrent attacks. In this article, we will present new therapeutic alternatives for long term prophylaxis. Glucocorticoids (GC) usage leads to a number of severe side-effects. In giant cell arteritis, the use of tocilizumab in conjunction with low doses of GC reduces the number of relapses. In ANCA-associated vasculitis the use of an anti-C5R (avacopan) alone or in conjunction with low doses of GC results in similar remission rates to those induced by high dose GC.
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PMID: 29337441
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Article (Published version) (179 Kb) - document accessible for UNIGE members only Limited access to UNIGE (until 2019-02-26)
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Research group La matrice extracellulaire (651)
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COATTRENEC, Yann et al. Allergologie et immunologie clinique. In: Revue médicale suisse, 2018, vol. 14, n° 588-589, p. 15-18. https://archive-ouverte.unige.ch/unige:102582

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Deposited on : 2018-02-28

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