Scientific article

High immunogenicity of delayed third dose of hepatitis B vaccine in travellers

Published inVaccine, vol. 25, no. 17, p. 3482-3484
Publication date2007

Travellers often present late for the third dose of hepatitis B vaccination and measuring anti-HBs serology is common practice to ensure that these individuals are protected. We assessed the adequacy of immune response in 86 healthy travellers who had their third dose of hepatitis B (HB) vaccine performed more than 1 year (median: 3.4 years; range: 1.1-10.5 years) after the second dose. Eighty-two travellers (95.3%) had evidence of sero-protection (anti-HBs titre >10 UI/L) including 16/17 (94.1%) travellers who had an interval of more than 5 years between second and third vaccine dose. We did not find any risk factor associated with insufficient response.

  • Adolescent
  • Adult
  • Female
  • Hepatitis B Antibodies/blood
  • Hepatitis B Vaccines/immunology
  • Humans
  • Immunization Schedule
  • Male
  • Middle Aged
  • Retrospective Studies
  • Time Factors
  • Travel
Citation (ISO format)
JACKSON, Yves-Laurent Julien et al. High immunogenicity of delayed third dose of hepatitis B vaccine in travellers. In: Vaccine, 2007, vol. 25, n° 17, p. 3482–3484. doi: 10.1016/j.vaccine.2006.12.053
Main files (1)
Article (Published version)
ISSN of the journal0264-410X

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