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Title

High immunogenicity of delayed third dose of hepatitis B vaccine in travellers

Authors
Kanappa, Kathi
Published in Vaccine. 2007, vol. 25, no. 17, p. 3482-3484
Abstract Travellers often present late for the third dose of hepatitis B vaccination and measuring anti-HBs serology is common practice to ensure that these individuals are protected. We assessed the adequacy of immune response in 86 healthy travellers who had their third dose of hepatitis B (HB) vaccine performed more than 1 year (median: 3.4 years; range: 1.1-10.5 years) after the second dose. Eighty-two travellers (95.3%) had evidence of sero-protection (anti-HBs titre >10 UI/L) including 16/17 (94.1%) travellers who had an interval of more than 5 years between second and third vaccine dose. We did not find any risk factor associated with insufficient response.
Keywords AdolescentAdultFemaleHepatitis B Antibodies/bloodHepatitis B Vaccines/immunologyHumansImmunization ScheduleMaleMiddle AgedRetrospective StudiesTime FactorsTravel
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PMID: 17306910
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JACKSON, Yves-Laurent Julien et al. High immunogenicity of delayed third dose of hepatitis B vaccine in travellers. In: Vaccine, 2007, vol. 25, n° 17, p. 3482-3484. https://archive-ouverte.unige.ch/unige:102463

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Deposited on : 2018-02-21

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