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Scientific article
English

Inhibitory role of oxytocin on TNFα expression assessed in vitro and in vivo

Publication date2017
Abstract

Oxytocin administration to diet-induced obese (DIO) rodents, monkeys and humans decreases body weight and fat mass with concomitant improvements in glucose metabolism. Moreover, several studies show an immunomodulatory role of oxytocin in a number of settings (such as atherosclerosis, injury, sepsis). This study aims to shed some light on the effects of oxytocin on macrophage polarization and cytokine production, as well as its possible impact on these parameters in adipose tissue in DIO mice with impaired glucose metabolism.

Keywords
  • Adipose tissue
  • Inflammation
  • Oxytocin
Citation (ISO format)
GARRIDO-URBANI, Sarah et al. Inhibitory role of oxytocin on TNFα expression assessed in vitro and in vivo. In: Diabetes & Metabolism, 2017. doi: 10.1016/j.diabet.2017.10.004
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Article (Published version)
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Identifiers
ISSN of the journal1262-3636
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