Inhibitory role of oxytocin on TNFα expression assessed in vitro and in vivo

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Title		Inhibitory role of oxytocin on TNFα expression assessed in vitro and in vivo
Authors		Garrido-Urbani, Sarah Deblon, N Poher, Anne-Laure Caillon, Aurélie Ropraz, Patricia Rohner-Jeanrenaud, Françoise Altirriba Gutierrez, Jorge
Published in		Diabetes & metabolism. 2017
Abstract		Oxytocin administration to diet-induced obese (DIO) rodents, monkeys and humans decreases body weight and fat mass with concomitant improvements in glucose metabolism. Moreover, several studies show an immunomodulatory role of oxytocin in a number of settings (such as atherosclerosis, injury, sepsis). This study aims to shed some light on the effects of oxytocin on macrophage polarization and cytokine production, as well as its possible impact on these parameters in adipose tissue in DIO mice with impaired glucose metabolism.
Keywords		Adipose tissue — Inflammation — Oxytocin
Identifiers		DOI: 10.1016/j.diabet.2017.10.004 PMID: 29129540
Full text		Article (Published version) (507 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
Citation (ISO format)		GARRIDO-URBANI, Sarah et al. Inhibitory role of oxytocin on TNFα expression assessed in vitro and in vivo. In: Diabetes & Metabolism, 2017. doi: 10.1016/j.diabet.2017.10.004 https://archive-ouverte.unige.ch/unige:102009

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Deposited on : 2018-02-09

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