Do Factor V Leiden and Prothrombin G20210A Mutations Predict Recurrent Venous Thromboembolism in Older Patients?

Méan, Marie; Limacher, Andreas; Stalder, Odile; Angelillo-Scherrer, Anne; Alberio, Lorenzo; Fontana, Pierre; Beer, Hans-Jürg; Rodondi, Nicolas; Lämmle, Bernhard; Aujesky, Drahomir

doi:10.1016/j.amjmed.2017.05.026

Scientific article

English

Do Factor V Leiden and Prothrombin G20210A Mutations Predict Recurrent Venous Thromboembolism in Older Patients?

ContributorsMéan, Marie; Limacher, Andreas; Stalder, Odile; Angelillo-Scherrer, Anne; Alberio, Lorenzo; Fontana, Pierre; Beer, Hans-Jürg; Rodondi, Nicolas; Lämmle, Bernhard; Aujesky, Drahomir

Published inAmerican Journal of Medicine, vol. 130, no. 10, p. 1220.e17-1220.e22

Publication date2017

Abstract

The value of genetic thrombophilia testing in elderly patients with an unprovoked venous thromboembolism is unclear. We assessed whether the Factor V Leiden and the prothrombin G20210A mutation are associated with recurrent venous thromboembolism in elderly patients in a prospective multicenter cohort study.

Keywords

Aged
Aged, 80 and over
Factor V/genetics
Female
Humans
Male
Mutation/genetics
Prospective Studies
Prothrombin/genetics
Recurrence
Risk Factors
Thrombophilia/complications/genetics
Venous Thromboembolism/etiology/genetics

Affiliation entities

Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Geneva Platelet Group (13)

Citation (ISO format)

MÉAN, Marie et al. Do Factor V Leiden and Prothrombin G20210A Mutations Predict Recurrent Venous Thromboembolism in Older Patients? In: American Journal of Medicine, 2017, vol. 130, n° 10, p. 1220.e17–1220.e22. doi: 10.1016/j.amjmed.2017.05.026

Article (Published version)

Identifiers

PID : unige:101839
DOI : 10.1016/j.amjmed.2017.05.026
PMID : 28606797

Journal ISSN0002-9343

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Do Factor V Leiden and Prothrombin G20210A Mutations Predict Recurrent Venous Thromboembolism in Older Patients?

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