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Title

Immune complexes containing serum B-cell activating factor and immunoglobulin G correlate with disease activity in systemic lupus erythematosus

Authors
Friebus-Kardash, Justa
Branco, Leonore
Huynh-Do, Uyen
Dubler, Denise
Dolff, Sebastian
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Published in Nephrology, Dialysis, Transplantation. 2017
Abstract B-cell activating factor belonging to the TNF family (BAFF) is important for the survival of autoreactive B-cells in systemic lupus erythematosus (SLE). However, the association between serum BAFF levels and SLE disease activity is controversial. Independently, autoantibodies targeting BAFF [immunoglobulin G (IgG) anti-BAFF] have also been described in SLE patients and were associated with increased disease activity. The aim of our study was to analyse the relationship between SLE disease manifestations and serum levels of BAFF, IgG anti-BAFF and BAFF-IgG complexes.
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PMID: 28992184
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Research group La matrice extracellulaire (651)
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FRIEBUS-KARDASH, Justa et al. Immune complexes containing serum B-cell activating factor and immunoglobulin G correlate with disease activity in systemic lupus erythematosus. In: Nephrology, Dialysis, Transplantation, 2017. https://archive-ouverte.unige.ch/unige:101827

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Deposited on : 2018-01-31

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