Combination of Gene Expression Signature and Model for End-stage Liver Disease Score Predicts Survival of Patients With Severe Alcoholic Hepatitis

Trépo, Eric; Goossens, Nicolas; Fujiwara, Naoto; Song, Won-Min; Colaprico, Antonio; Marot, Astrid; Spahr, Laurent François Joséph; Demetter, Pieter; Sempoux, Christine; Im, Gene Y; Saldarriaga, Joan; Gustot, Thierry; Devière, Jacques; Thung, Swan N; Minsart, Charlotte; Sersté, Thomas; Bontempi, Gianluca; Abdelrahman, Karim; Henrion, Jean; Degré, Delphine; Lucidi, Valerio; Rubbia-Brandt, Laura; Nair, Venugopalan D; Moreno, Christophe; Deltenre, Pierre; Hoshida, Yujin; Franchimont, Denis

doi:10.1053/j.gastro.2017.10.048

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Title		Combination of Gene Expression Signature and Model for End-stage Liver Disease Score Predicts Survival of Patients With Severe Alcoholic Hepatitis
Authors		Trépo, Eric Goossens, Nicolas Fujiwara, Naoto Song, Won-Min Colaprico, Antonio Marot, Astrid Spahr, Laurent François Joséph Demetter, Pieter Sempoux, Christine Im, Gene Y Saldarriaga, Joan Gustot, Thierry Devière, Jacques Thung, Swan N Minsart, Charlotte Sersté, Thomas Bontempi, Gianluca Abdelrahman, Karim Henrion, Jean Degré, Delphine Lucidi, Valerio Rubbia-Brandt, Laura Nair, Venugopalan D Moreno, Christophe Deltenre, Pierre Hoshida, Yujin Franchimont, Denis show all authors [1 - 27]
Published in		Gastroenterology. 2017
Abstract		Patients with severe alcoholic hepatitis (AH) have a high risk of death within 90 days. Corticosteroids, which can cause severe adverse events, are the only treatment that increases short-term survival. It is a challenge to predict outcomes of patients with severe AH. Therefore, we developed a scoring system to predict patient survival, integrating baseline molecular and clinical variables.
Identifiers		DOI: 10.1053/j.gastro.2017.10.048 PMID: 29158192
Full text		Article (Accepted version) (5.2 MB) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
Research group		Métastases du foie (657)
Citation (ISO format)		TRÉPO, Eric et al. Combination of Gene Expression Signature and Model for End-stage Liver Disease Score Predicts Survival of Patients With Severe Alcoholic Hepatitis. In: Gastroenterology, 2017. doi: 10.1053/j.gastro.2017.10.048 https://archive-ouverte.unige.ch/unige:101477