Scientific article
English

Low threshold calcium spikes in medial vestibular nuclei neurones in vitro: a role in the generation of the vestibular nystagmus quick phase in vivo?

Published inExperimental brain research, vol. 82, no. 1, p. 187-190
Publication date1990
Abstract

Intracellular recordings were obtained from medial vestibular nuclei neurones in guinea-pig brainstem slices. A subpopulation of neurones in this nucleus was found to have burst firing properties. Using ionic channel blockers the underlying mechanism was shown to be a low threshold calcium spike. It is speculated that this property could be implicated in the generation of the quick phase of the vestibular nystagmus in the behaving guinea-pig.

Keywords
  • Action Potentials/physiology
  • Animals
  • Brain Stem/cytology/physiology
  • Calcium/ physiology
  • Calcium Channel Blockers/pharmacology
  • Cerebellum/cytology/physiology
  • Guinea Pigs
  • Neurons/drug effects/ physiology
  • Nystagmus, Physiologic/ physiology
  • Ocular Physiological Phenomena
  • Reflex/physiology
  • Tetrodotoxin/pharmacology
  • Thalamus/cytology/physiology
  • Vestibular Nuclei/cytology/ physiology
Citation (ISO format)
SERAFIN, Mauro et al. Low threshold calcium spikes in medial vestibular nuclei neurones in vitro: a role in the generation of the vestibular nystagmus quick phase in vivo? In: Experimental brain research, 1990, vol. 82, n° 1, p. 187–190.
Identifiers
ISSN of the journal0014-4819
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