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Low threshold calcium spikes in medial vestibular nuclei neurones in vitro: a role in the generation of the vestibular nystagmus quick phase in vivo?

Khateb, A.
de Waele, C.
Vidal, P. P.
Published in Experimental Brain Research. 1990, vol. 82, no. 1, p. 187-190
Abstract Intracellular recordings were obtained from medial vestibular nuclei neurones in guinea-pig brainstem slices. A subpopulation of neurones in this nucleus was found to have burst firing properties. Using ionic channel blockers the underlying mechanism was shown to be a low threshold calcium spike. It is speculated that this property could be implicated in the generation of the quick phase of the vestibular nystagmus in the behaving guinea-pig.
Keywords Action Potentials/physiologyAnimalsBrain Stem/cytology/physiologyCalcium/ physiologyCalcium Channel Blockers/pharmacologyCerebellum/cytology/physiologyGuinea PigsNeurons/drug effects/ physiologyNystagmus, Physiologic/ physiologyOcular Physiological PhenomenaReflex/physiologyTetrodotoxin/pharmacologyThalamus/cytology/physiologyVestibular Nuclei/cytology/ physiology
Stable URL http://archive-ouverte.unige.ch/unige:10125
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PMID: 2257903

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Deposited on : 2010-08-06

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