Scientific article

Medial vestibular nucleus in the guinea-pig. I. Intrinsic membrane properties in brainstem slices

Published inExperimental brain research, vol. 84, no. 2, p. 417-425
Publication date1991

Intracellular recordings were obtained from medial vestibular nuclei neurones (MVNn) in guinea-pig brainstem slices. Two main distinct neuronal classes were encountered. Type A MVNn (32.3%) were characterized by a broad action potential followed by a deep single afterhyperpolarization, a transient A-like rectification, and a single range of firing in response to current injection. Type B MVNn (47.1%), in contrast, were distinguished by the presence of a thin action potential followed first by a fast and then by a delayed and slower afterhyperpolarization. In addition, they displayed a secondary range of firing in their response to current injection. A majority of B MVNn also had either sub-threshold plateau potentials or low threshold spike bursts or a combination thereof. A third, non-homogeneous class of cells, could not be fitted into either one of the two main classes (20.6%, type C MVNn).

  • Action Potentials
  • Animals
  • Brain Stem/anatomy & histology/ physiology
  • Cell Membrane/physiology
  • Evoked Potentials
  • Guinea Pigs
  • Neurons/ physiology
  • Vestibular Nuclei/anatomy & histology/ physiology
Citation (ISO format)
SERAFIN, Mauro et al. Medial vestibular nucleus in the guinea-pig. I. Intrinsic membrane properties in brainstem slices. In: Experimental brain research, 1991, vol. 84, n° 2, p. 417–425. doi: 10.1007/bf00231464
ISSN of the journal0014-4819

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