en
Scientific article
English

Study on the mathematical relationship existing between single-photon laser-Doppler flowmetry and diffuse correlation spectroscopy with static background

Publication date2017
Abstract

In the present contribution, the theoretical relationship existing between the blood flow index measured by diffuse correlation spectroscopy and single-photon laser-Doppler flowmetry (SP-LDF) is investigated. A specific mathematical description that accounts for the properties of single-photon detectors for SP-LDP was developed. Static background has also been considered and, to the best of our knowledge, this has never been included before in SP-LDF analytical theories. The comparisons were realized for two SP-LDF implementations: for "classical" and "fast" algorithms. "Classical" SP-LDF is not sensitive to small changes on the number of detected speckles and coherence length of the laser, usually described by a unique parameter "beta." This is a strong point when assessing blood flow index, e.g., in humans, where "beta" is particularly difficult to be determined in real time. The proposed theory may be utilized, e.g., to investigate other SP-LDF setups and optical/physiological parameter ranges or, generally, to optimize real SP-LDF instrumentation.

Citation (ISO format)
BINZONI, Tiziano, MARTELLI, Fabrizio. Study on the mathematical relationship existing between single-photon laser-Doppler flowmetry and diffuse correlation spectroscopy with static background. In: Journal of the Optical Society of America. A: Optics, Image Science, and Vision, 2017, vol. 34, n° 12, p. 2096–2101.
Identifiers
ISSN of the journal1084-7529
380views
0downloads

Technical informations

Creation12/15/2017 7:53:00 PM
First validation12/15/2017 7:53:00 PM
Update time03/15/2023 7:41:35 AM
Status update03/15/2023 7:41:35 AM
Last indexation01/17/2024 1:55:34 AM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack