Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolism
Published inPLOS ONE, vol. 12, no. 4, e0176391
Publication date2017
Abstract
Keywords
- Diabetes Mellitus, Type 2/metabolism
- Female
- Gene Expression Regulation/drug effects
- Glucose/metabolism
- Humans
- Insulin/secretion
- Islets of Langerhans/drug effects/metabolism/secretion
- Lipid Metabolism/drug effects
- Male
- Middle Aged
- Palmitates/pharmacology
- Proinsulin/metabolism
- Proteomics
- Time Factors
Research group
Citation (ISO format)
ROOMP, Kirsten et al. Combined lipidomic and proteomic analysis of isolated human islets exposed to palmitate reveals time-dependent changes in insulin secretion and lipid metabolism. In: PLOS ONE, 2017, vol. 12, n° 4, p. e0176391. doi: 10.1371/journal.pone.0176391
Main files (1)
Article (Published version)
Identifiers
- PID : unige:100598
- DOI : 10.1371/journal.pone.0176391
- PMID : 28448538
ISSN of the journal1932-6203