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The Lausanne-Geneva cohort study of offspring of parents with mood disorders: methodology, findings, current sample characteristics, and perspectives

Published inSocial Psychiatry and Psychiatric Epidemiology, vol. 52, no. 8, p. 1041-1058
Publication date2017
Abstract

Studies focusing on the offspring of affected parents utilize the well-established familial aggregation of mood disorders as a powerful tool for the identification of risk factors, early clinical manifestations, and prodromes of mood disorders in these offspring. The major goals of the Lausanne-Geneva mood cohort study are to: (1) assess the familial aggregation of bipolar and unipolar mood disorders; (2) prospectively identify risk factors for mood disorders as well as their early signs and prodromes; (3) identify their endophenotypes including cognitive features, alterations in brain structure, HPA-axis dysregulation, and abnormalities of the circadian rhythm of activity.

Citation (ISO format)
VANDELEUR, Caroline L et al. The Lausanne-Geneva cohort study of offspring of parents with mood disorders: methodology, findings, current sample characteristics, and perspectives. In: Social Psychiatry and Psychiatric Epidemiology, 2017, vol. 52, n° 8, p. 1041–1058. doi: 10.1007/s00127-017-1382-0
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ISSN of the journal0933-7954
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