Other version: https://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-1024624
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Scientific Article
unige:10030 
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Metabolic transient studies by NMR |
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| Authors | ||
| Published in | International Journal of Sports Medicine. 1992, vol. 13, no. Suppl 1, p. S155-157 | |
| Abstract | The time course of phosphocreatine (PC) hydrolysis in humans was measured by 31P-NMR spectroscopy (31P-NMRS) with a time resolution of 10.8 s in the gastrocnemius muscle and a relationship between muscle O2 consumption (VO2) and [PC] was derived from a bioenergetic model. This allowed a direct estimate of the half-time of the intracellular VO2 kinetics (t1/2 VO2) of the contracting human gastrocnemius in aerobic conditions. t1/2 VO2 was found to be approximately 16 s and independent of the work load. This value corresponds to the shortest t1/2 VO2 determined at the mouth of the subject in the absence of lactate accumulation in the rest to work transient. t1/2 VO2 may now be assessed in man at low muscle temperatures. To this aim a procedure was developed allowing corrections of the 31P-NMR spectra based on the muscle temperature profiles obtained by a simultaneously acquired proton image. | |
| Keywords | Adenosine Triphosphate/biosynthesis — Body Temperature/physiology — Energy Metabolism/physiology — Exercise/physiology — Humans — Hydrolysis — Magnetic Resonance Spectroscopy — Muscles/ metabolism — Oxygen Consumption/physiology — Phosphocreatine/metabolism | |
| Identifiers | PMID: 1483759 | |
| Full text | ||
| Citation (ISO format) | BINZONI, Tiziano et al. Metabolic transient studies by NMR. In: International Journal of Sports Medicine, 1992, vol. 13, n° Suppl 1, p. S155-157. https://archive-ouverte.unige.ch/unige:10030 |
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