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Title

Ventral striatal hypoactivation is associated with apathy but not diminished expression in patients with schizophrenia

Authors
Kirschner, Matthias
Hager, Oliver M
Bischof, Martin
Hartmann, Matthias N
Kluge, Agne
Seifritz, Erich
Tobler, Philippe N
Published in Journal of Psychiatry and Neuroscience. 2016, vol. 41, no. 3, p. 152-61
Abstract Negative symptoms of schizophrenia can be grouped in 2 dimensions: apathy and diminished expression. Increasing evidence suggests that negative symptoms are associated with altered neural activity of subcortical and cortical regions in the brain reward system. However, the neurobiological basis of the distinct symptom dimensions within negative symptoms is still poorly understood. The primary aim of our study was to examine the neural correlates of the negative symptom dimensions apathy and diminished expression during a reward processing task.
Identifiers
PMID: 26395814
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KIRSCHNER, Matthias et al. Ventral striatal hypoactivation is associated with apathy but not diminished expression in patients with schizophrenia. In: Journal of Psychiatry and Neuroscience, 2016, vol. 41, n° 3, p. 152-61. https://archive-ouverte.unige.ch/unige:100248

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Deposited on : 2017-12-13

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