Encompassing the Complexity of Personality to Understand its Association with Disability in Multiple Sclerosis

Article Article scientifique Article Encompassing the Complexity of Personality to Understand its Association with Disability in Multiple Sclerosis eng 2026-07-18 author Jacot De Alcantara Isabele Harumi 0000-0002-2033-6287 837619 Section de psychologie (PSICO) author Baldoni Valerio 989536 Département des neurosciences cliniques (OTONO) author Voruz Philippe 0000-0001-6796-8807 804968 Section de psychologie (PSICO) author Allali Gilles 507314 Département des neurosciences cliniques (OTONO) author Lalive d'Epinay Patrice 636926 Département des neurosciences cliniques (OTONO) author Peron Julie Anne 705680 Section de psychologie (PSICO) 10.1177/13591053261463104 42470267 1359-1053 https://journals.sagepub.com/doi/10.1177/13591053261463104 While specific personality traits have been associated with disability in multiple sclerosis (MS), less is known about how combinations of these traits relate to disability. This study explored personality profiles in people living with MS (PwMS) and their associations with disability. Eighty-two PwMS (55 women, 27 men; mean age = 45.7 years) were assessed using the NEO-Personality Inventory-3rd edition, the Expanded Disability Status Scale, and the World Health Organization Disability Assessment Schedule 2.0. Cluster analysis including thirty personality facets identified two profiles, labeled Resilient and Sensitive. People with the Resilient profile tend to be more optimistic, goal-directed, and proactive. Mean comparison analyses revealed that individuals with the Resilient profile showed lower observed and perceived disability, particularly in cognitive, social, and life activity domains. Our results highlight the importance of adopting a profile-based and facet-level perspective on personality, as relying solely on broad traits may be reductionist. Multiple sclerosis Personality Individual differences Cluster analysis Disability Dewey 616.8 Dewey 150 108 Section de psychologie 71 61 Département des neurosciences cliniques 226 false 1409 Neuropsychologie clinique et expérimentale (CENLab) 505 Scléroses en plaques, neuroimmunologie, encéphalite autoimmune expérimentale 843 Journal of health psychology abecc989-1cf1-4453-9586-3be23a941e20 Article (Accepted version) Public Jacot_de_Alcântara_et_al._(2026)._E.pdf 314103 application/pdf 3bfe543a3002bf8e28b87e909b2c7505659d6dc41a418c06cb6f660889dd7084 ca0d108f-964f-44e1-aba2-73c100accd7d Appendix Public sj-docx-1-hpq-10.1177_1359105326146.docx 308919 application/vnd.openxmlformats-officedocument.wordprocessingml.document d8971357c07819e486a43d4c9f9548084b84d33224372afd1a6050ebfcd0a3ae eb8f01b8-45f3-45f5-bced-22d49eb97200 Article (Published version) Restricted jacot-de-alcântara-et-al-2026-encom.pdf 372217 application/pdf aee81d163f34273dc2546e70ace6776afeb62f1f56402de869f83cc7273182fc openAccess Faculté de psychologie et des sciences de l'éducation / Section de psychologie Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques

Title	Published in	Year	Views	Downloads

Encompassing the Complexity of Personality to Understand its Association with Disability in Multiple Sclerosis	Journal of health psychology	2026	1	0
Ce n’est pas mon corps ! La conscience du soi-corporel perturbée chez les patients neurologiques		2024	101	6

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Baldoni, Valerio

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