European intersocietal recommendations for the biomarker-based diagnosis of neurocognitive disorders

Article Article scientifique Revue de la littérature European intersocietal recommendations for the biomarker-based diagnosis of neurocognitive disorders eng 2024-03 author Frisoni Giovanni Laboratory of Neuroimaging of Aging (LANVIE), University of Geneva, Geneva, Switzerland; Geneva Memory Center, Department of Rehabilitation and Geriatrics, Geneva University Hospitals, Geneva, Switzerland. Electronic address: giovanni.frisoni@unige.ch. 810190 dept de réadaptation et gériatrie (MIGRG) author Festari Cristina Laboratory of Alzheimer's Neuroimaging and Epidemiology, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy. author Massa Federico Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa, Italy. author Cotta Ramusino Matteo Unit of Behavioral Neurology and Dementia Research Center (DRC), IRCCS Mondino Foundation, Pavia, Italy. author Orini Stefania Alzheimer's Unit-Memory Clinic, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy; Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy. author Aarsland Dag Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, Norway; UK Dementia Research Institute, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK. author Agosta Federica Neuroimaging Research Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, Italy. author Babiloni Claudio Department of Physiology and Pharmacology "V Erspamer", Sapienza University of Rome, Rome, Italy; Hospital San Raffaele of Cassino, Cassino, Italy. author Borroni Barbara Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy; Department of Continuity of Care and Frailty, ASST Spedali Civili, Brescia, Italy. author Cappa Stefano Centro Ricerca sulle Demenze, IRCCS Mondino Foundation, Pavia, Italy; University Institute for Advanced Studies (IUSS), Pavia, Italy. 983792 author Frederiksen Kristian S Danish Dementia Research Centre, Department of Neurology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark. author Froelich Lutz Department of Geriatric Psychiatry, Central Institute of Mental Health Mannheim, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany. author Garibotto Valentina 0000-0003-2422-698X Laboratory of Neuroimaging and Innovative Molecular Tracers (NIMTlab), Geneva University Neurocenter and Faculty of Medicine, University of Geneva, Geneva, Switzerland; Division of Nuclear Medicine and Molecular Imaging, Geneva University Hospitals, Geneva, Switzerland; CIBM Center for Biomedical Imaging, Geneva, Switzerland. 704817 Département de radiologie et informatique médicale (RADIO) author Haliassos Alexander ESEAP-Proficiency Testing Scheme for Clinical Laboratories, Athens, Greece. author Jessen Frank German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany; Department of Psychiatry, University of Cologne, Medical Faculty, Cologne, Germany; Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany. author Kamondi Anita National Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary; Department of Neurology, Semmelweis University, Budapest, Hungary. author Kessels Roy Pc Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, Netherlands; Radboud UMC Alzheimer Center and Department of Medical Psychology, Radboud University Medical Center, Nijmegen, Netherlands; Vincent van Gogh Institute for Psychiatry, Venray, Netherlands. author Morbelli Silvia D Department of Health Sciences (DISSAL), University of Genoa, Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa, Italy. author O'Brien John T Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, UK. author Otto Markus Department of Neurology, Martin Luther University of Halle-Wittenberg, Halle (Saale), Germany. author Perret-Liaudet Armand Neurobiology, Hospices Civils de Lyon, Lyon, France. author Pizzini Francesca B Department of Diagnostic and Public Health, Verona University Hospital, Verona University, Verona, Italy. author Vandenbulcke Mathieu Department of Neurosciences, KU Leuven, Leuven, Belgium; Department of Geriatric Psychiatry, University Psychiatric Centre KU Leuven, Leuven-Kortenberg, Belgium. author Vanninen Ritva University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland. author Verhey Frans Department of Psychiatry and Neuropsychology-Alzheimer Centre Limburg, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands. author Vernooij Meike W Department of Epidemiology and Department of Radiology and Nuclear Medicine Erasmus MC University Medical Center, Rotterdam, Netherlands. author Yousry Tarek Lysholm Department of Neuroradiology and the Neuroradiological Academic Unit, Department of Brain Repair and Rehabilitation, University College London Hospitals NHS Foundation Trust National Hospital for Neurology and Neurosurgery, London, UK. author Boada Rovira Mercè Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, Spain. author Dubois Hervé Christian Bruno Institut de La Mémoire et de La Maladie d'Alzheimer, Neurology Department, Salpêtrière Hospital, Assistance Publique-Hôpital de Paris, Paris, France; Sorbonne University, Paris, France. 28190 author Georges Jean-Claude Denis M. Alzheimer Europe, Luxembourg. 32346 author Hansson Oskar Clinical Memory Research Unit, Department of Clinical Sciences, Lund University, Malmö, Sweden; Memory Clinic, Skåne University Hospital, Malmö, Sweden. author Ritchie Craig W Edinburgh Dementia Prevention, Centre for Clinical Brain Sciences, Western General Hospital, University of Edinburgh, Edinburgh, UK; Brain Health Scotland, Edinburgh, UK. author Scheltens Philip Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, Netherlands. author van der Flier Wiesje M Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, Netherlands; Amsterdam Neuroscience-Neurodegeneration, Amsterdam, Netherlands; Epidemiology and Data Science, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, Netherlands. author Nobili Flavio Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), University of Genoa, Genoa, Italy; IRCCS Ospedale Policlinico San Martino, Genoa, Italy. 302-312 10.1016/S1474-4422(23)00447-7 38365381 1474-4422 https://www.sciencedirect.com/science/article/pii/S1474442223004477 The recent commercialisation of the first disease-modifying drugs for Alzheimer's disease emphasises the need for consensus recommendations on the rational use of biomarkers to diagnose people with suspected neurocognitive disorders in memory clinics. Most available recommendations and guidelines are either disease-centred or biomarker-centred. A European multidisciplinary taskforce consisting of 22 experts from 11 European scientific societies set out to define the first patient-centred diagnostic workflow that aims to prioritise testing for available biomarkers in individuals attending memory clinics. After an extensive literature review, we used a Delphi consensus procedure to identify 11 clinical syndromes, based on clinical history and examination, neuropsychology, blood tests, structural imaging, and, in some cases, EEG. We recommend first-line and, if needed, second-line testing for biomarkers according to the patient's clinical profile and the results of previous biomarker findings. This diagnostic workflow will promote consistency in the diagnosis of neurocognitive disorders across European countries. Humans Alzheimer Disease / diagnosis Europe Biomarkers Consensus Societies, Scientific Dewey 616.0757 Dewey 618.97 Swiss National Science Foundation The Biological Basis of Cognitive Impairment due to Suspected Non-Alzheimer’s Pathology (SNAP) : Studying the interplay between amyloidosis and tau-related neurodegeneration 169876 CH Projects Swiss National Science Foundation Individual cognitive risk profiling in aging according to Amyloid, Tau and Neurodegeneration imaging biomarkers 185028 CH Projects Swiss National Science Foundation Strategic roadmap for the translation of tau biomarkers in the clinic: an international task force 188355 CH Science communication 62 Département de radiologie et informatique médicale 227 65 Département de réadaptation et gériatrie 22B false 1222 Laboratoire de neuroimagerie et de traceurs moléculaires innovants 984 853 Troubles de mémoire et maladie d'Alzeimer 935 Lancet neurology 23 3 b9958ed2-d274-45b7-acfe-1f55665b177a Article (Published version) Restricted 1-s2.0-S1474442223004477-main.pdf 377110 application/pdf d403438bf9435cabff2b3d2bc6469f98e2c1278a94911a362df90bbe2770118a aed16ca5-15e5-4e95-8fe3-e3afff3e14bc Supplemental data Restricted 1-s2.0-S1474442223004477-mmc1.pdf 563452 application/pdf 40349f610974efc876a9fe0495e12f6779a7d381c3a22c2ab71857f7adab625c restrictedAccess Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie

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