Three-Dimensional Reconstruction of Basal Cell Carcinomas

Article Article scientifique Revue de la littérature Three-Dimensional Reconstruction of Basal Cell Carcinomas eng 2005-05 author Braun Ralph 95787 author Klumb Francis 563232 author Bondon David author Salomon Denis 26290 author Skaria Andreas author Adatto Maurice Alfred 64980 author French Lars 32969 author Saurat Jean-Hilaire 21995 Décanat et administration de la faculté de médecine (ADMED) author Vallée Jean-Paul 0000-0001-7546-2013 29185 Département de radiologie et informatique médicale (RADIO) 562-568 10.1111/j.1524-4725.2005.31162 15962742 1076-0512 https://journals.lww.com/dermatologicsurgery/Fulltext/2005/05000/Three_Dimensional_Reconstruction_of_Basal_Cell.13.aspx Background: Basal cell carcinoma (BCC) is the most common type of skin cancer. One of the main problems with BCC is the risk of local recurrence of the tumor after treatment. This is mainly due to its irregular outgrowths, which cannot be detected clinically. Objective: To better understand the tumor morphology and growth pattern of BCC, we tried to develop a method that provides a precise three-dimensional model of the tumor. Methods: Because Mohs surgery provides the best overview of the tumor and the tumor margins (both lateral and in depth), the reconstruction was based on slides from Mohs surgery. After digitization and processing of the slides, the tumor was then surrounded by a Mohs surgeon on a computer screen. These selections (lines) were used for a three-dimensional reconstruction of the tumor using MedSurf3D software. Results: This method allows three-dimensional reconstruction of any given BCC. The MedSurf3D software enables visualization of a three-dimensional model of the tissue, which is removed during the surgical procedure. Conclusions: Three-dimensional reconstruction is a fascinating tool that might improve our understanding of the behavior, growth pattern, and tumor morphology of BCCs. This technique might also be useful in other fields of cutaneous oncology, such as the calculation of the tumor volume of melanomas. Carcinoma, Basal Cell / pathology Carcinoma, Basal Cell / surgery Humans Image Processing, Computer-Assisted Mohs Surgery / methods Skin Neoplasms / pathology Skin Neoplasms / surgery Dewey 616.0757 Dewey 616 62 Département de radiologie et informatique médicale 227 56 Département de médecine 221 false 286 Imagerie cardiaque fonctionnelle 541 Dermatologic surgery 31 5 5cc54c76-669c-48f8-9cd4-b316e219be32 Article (Published version) Restricted THREE DIMENSIONAL RECONSTRUCTION OF.pdf 1234727 application/pdf 54c49fac969054e300f19b9b06b379881966d6dc11e037523cab7bd17a04f7fe restrictedAccess Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale Faculté de médecine / Section de médecine clinique / Département de médecine

Title	Published in	Year	Views	Downloads

Three-Dimensional Reconstruction of Basal Cell Carcinomas	Dermatologic surgery	2005	99	0
Kaposi's sarcoma: a new approach of lesional follow-up using epiluminescent light microscopy	Dermatology	1999	230	0

Archive ouverte UNIGE

Braun, Ralph