Lower risk of peripheral venous catheter-related bloodstream infection by hand insertion

Article Article scientifique Article Lower risk of peripheral venous catheter-related bloodstream infection by hand insertion eng 2022-06-03 2022-06-03 author Buetti Niccolo 954325 author Abbas Mohamed 0000-0002-7265-1887 528404 author Pittet Didier 117792 author Chraiti Marie-Noëlle 526954 author Sauvan Valérie 526970 author De Kraker Marlieke 0000-0003-0903-8614 836719 author Boisson Matthieu 951299 author Teixeira Daniel 798512 author Zingg Walter 654437 author Harbarth Stéphan Juergen 0000-0002-3551-1025 93885 80 10.1186/s13756-022-01117-8 35659775 2047-2994 PMC9164319 https://aricjournal.biomedcentral.com/articles/10.1186/s13756-022-01117-8 Introduction: Little is known about the bloodstream infection (BSI) risk associated with short-term peripheral venous catheters (PVCs) and no large study investigated the insertion site-related risk for PVC-BSI. Methods: We performed a cohort study at the University of Geneva Hospitals using the prospective hospital-wide BSI surveillance database. We analyzed the association between insertion site and risk of PVC-BSI on the upper extremity using univariable and multivariable marginal Cox models. Results: Between 2016 and 2020, utilization of 403'206 peripheral venous catheters were prospectively recorded in a 2000-bed hospital consortium with ten sites. Twenty-seven percent of PVC (n = 109'686) were inserted in the hand. After adjustment for confounding factors, hand insertion was associated with a decreased PVC-BSI risk (adjusted hazard ratio [HR] 0.42, 95% CI 0.18-0.98, p = 0.046) compared to more proximal insertion sites. In a sensitivity analysis for PVCs with = 3 days of dwell time, we confirmed a decreased PVC-BSI risk after hand insertion (HR 0.37, 95% CI 0.15-0.93, p = 0.035). Conclusion: Hand insertion should be considered for reducing PVC infections, especially for catheters with an expected dwell time of more than 2 days. Bloodstream infections Catheter Catheter-infection Insertion site Peripheral venous catheters Catheter-Related Infections / epidemiology Catheters Cohort Studies Cross Infection / epidemiology Humans Polyvinyl Chloride Prospective Studies Sepsis / epidemiology Dewey 616 Swiss National Science Foundation Epidemiology and determinants of catheter-related and hospital-acquired bloodstream infections: from a large university hospital to a global picture 194449 CH Careers European Commission Combatting Bacterial Resistance in Europe 115523 COMBACTE-NET EU FP7 56 Département de médecine 221 false 526 Résistance aux antibiotiques 866 Antimicrobial resistance and infection control 11 1 0f5a61f1-0675-48a3-bdbb-fdb368982b0b Article (Published version) Public Article-scientifique-from-europePmc.pdf 1009461 application/pdf CC BY-4.0 d833dc9b-2cdc-4cb1-8a36-22ea0ca2e90d Appendix Public 13756_2022_1117_Fig1_HTML.jpg 78266 image/jpeg Figure 1 (Flow-chart) 8965ad10-fc25-4764-8ea5-84c0e3db6bc6 Appendix Public 13756_2022_1117_Fig2_HTML.jpg 40928 image/jpeg Figure 2 d4911b60-f857-4728-8e80-e2957861cc89 Appendix Public 13756_2022_1117_MOESM1_ESM.docx 17771 application/vnd.openxmlformats-officedocument.wordprocessingml.document Tables S1, S2, S3, S4, S5 openAccess Faculté de médecine / Section de médecine clinique / Département de médecine

Title	Published in	Access level	OA Policy	Year	Views	Downloads

Lower risk of peripheral venous catheter-related bloodstream infection by hand insertion	Antimicrobial resistance and infection control			2022	214	170

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