Bioinspired Ether Cyclizations within a π‐Basic Capsule Compared to Autocatalysis on π‐Acidic Surfaces and Pnictogen‐Bonding Catalysts

Article Article scientifique Article Bioinspired Ether Cyclizations within a π‐Basic Capsule Compared to Autocatalysis on π‐Acidic Surfaces and Pnictogen‐Bonding Catalysts eng 2021 author Hao Xiaoyu 895525 author Li Tian‐Ren author Chen Hao 944302 author Gini Andrea 910395 author Zhang Xiang 873627 author Rosset Stéphane 28170 author Mazet Clement 0000-0002-2385-280X 667534 author Tiefenbacher Konrad author Matile Stefan 0000-0002-8537-8349 129654 12215-12223 10.1002/chem.202101548 0947-6539 https://onlinelibrary.wiley.com/doi/10.1002/chem.202101548 While the integration of supramolecular principles in catalysis attracts increasing attention, a direct comparative assessment of the resulting systems catalysts to work out distinct characteristics is often difficult. Herein is reported how the broad responsiveness of ether cyclizations to diverse inputs promises to fill this gap. Cyclizations in the confined, π-basic and Brønsted acidic interior of supramolecular capsules, for instance, are found to excel with speed (exceeding general Brønsted acid and hydrogen-bonding catalysts by far) and selective violations of the Baldwin rules (as extreme as the so far unique pnictogen-bonding catalysts). The complementary cyclization on π-acidic aromatic surfaces remains unique with regard to autocatalysis, which is shown to be chemo- and diastereoselective with regard to product-like co-catalysts but, so far, not enantioselective. Dewey 540 36 Département de chimie organique 141 false 761 Groupe Matile 763 Groupe Mazet Chemistry - A European Journal 27 47 62a98230-837b-48bb-8f1a-3889b5dd119e Article (Published version) Public chem.202101548.pdf 7127900 application/pdf CC BY openAccess Faculté des sciences / Section de chimie et biochimie / Département de chimie organique

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Bioinspired Ether Cyclizations within a π‐Basic Capsule Compared to Autocatalysis on π‐Acidic Surfaces and Pnictogen‐Bonding Catalysts	Chemistry - A European Journal			2021	527	182

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