| A novel mitochondrial pyruvate carrier inhibitor drives stem cell-like memory CAR T cell generation and enhances antitumor efficacy | Molecular therapy. Oncology |  | | 2024 | 216 | 189 |
|
| First full views of a CRISPR-guided system for gene insertion | Nature |  | | 2023 | 78 | 0 |
|
| Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomes | Nucleic acids research | | | 2022 | 91 | 50 |
|
| Engineered Sleeping Beauty transposase redirects transposon integration away from genes | Nucleic acids research | | | 2022 | 71 | 46 |
|
| Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomes | Molecular systems biology | | | 2021 | 145 | 396 |
|
| Towards Dissecting the Mechanism of Protein Phosphatase‐1 Inhibition by Its C ‐Terminal Phosphorylation | ChemBioChem | | | 2020 | 68 | 39 |
|
| A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogramming | Nucleic acids research | | | 2020 | 105 | 72 |
|
| A highly soluble Sleeping Beauty transposase improves control of gene insertion | Nature biotechnology | | | 2019 | 98 | 0 |
|
| The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans | Genes & development | | | 2019 | 99 | 37 |
|
| Snapshots of a genetic cut-and-paste | Nature | | | 2019 | 80 | 0 |
|
| Jump ahead with a twist: DNA acrobatics drive transposition forward | Current opinion in structural biology | | | 2019 | 72 | 109 |
|
| Conjugative transposition of the vancomycin resistance carrying Tn1549: enzymatic requirements and target site preferences | Molecular microbiology | | | 2018 | 64 | 33 |
|
| Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering | Nucleic acids research | | | 2018 | 97 | 34 |
|
| Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance | Cell | | | 2018 | 112 | 50 |
|
| Effects of stably incorporated iron on protein phosphatase‐1 structure and activity | FEBS letters | | | 2018 | 81 | 87 |
|
| Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq | Scientific reports | | | 2017 | 65 | 35 |
|
| Structural Determinants of Sleeping Beauty Transposase Activity | Molecular therapy | | | 2016 | 85 | 23 |
|
| Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering | Nature communications | | | 2016 | 86 | 140 |
|
| Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending | eLife | | | 2016 | 93 | 38 |
|
| An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilum | Nucleic Acids Research | | | 2014 | 192 | 194 |
|
| Structure of an Escherichia coli Hfq:RNA complex at 0.97 Å resolution | Acta crystallographica. Section F, Structural biology communications | | | 2014 | 70 | 0 |
|
| Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modelling | Nucleic acids research | | | 2013 | 87 | 32 |
|
| Acquisition of an Archaea-like ribonuclease H domain by plant L1 retrotransposons supports modular evolution | Proceedings of the National Academy of Sciences of the United States of America | | | 2013 | 61 | 0 |
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