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A novel mitochondrial pyruvate carrier inhibitor drives stem cell-like memory CAR T cell generation and enhances antitumor efficacyMolecular therapy. Oncology
accessLevelPublic
2024 105 91
First full views of a CRISPR-guided system for gene insertionNature
accessLevelRestricted
2023 63 0
Landscape of mobile genetic elements and their antibiotic resistance cargo in prokaryotic genomesNucleic Acids Research
accessLevelPublic
2022 70 14
Engineered Sleeping Beauty transposase redirects transposon integration away from genesNucleic Acids Research
accessLevelPublic
2022 50 22
Sequence analysis of tyrosine recombinases allows annotation of mobile genetic elements in prokaryotic genomesMolecular systems biology
accessLevelPublic
2021 90 60
Towards Dissecting the Mechanism of Protein Phosphatase‐1 Inhibition by Its C ‐Terminal PhosphorylationChemBioChem
accessLevelPublic
2020 47 16
A single amino acid switch converts the Sleeping Beauty transposase into an efficient unidirectional excisionase with utility in stem cell reprogrammingNucleic acids research
accessLevelPublic
2020 87 35
A highly soluble Sleeping Beauty transposase improves control of gene insertionNature biotechnology
accessLevelRestricted
2019 78 0
The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegansGenes & development
accessLevelPublic
2019 80 18
Snapshots of a genetic cut-and-pasteNature
accessLevelRestricted
2019 62 0
Jump ahead with a twist: DNA acrobatics drive transposition forwardCurrent opinion in structural biology
accessLevelPublic
2019 55 36
Conjugative transposition of the vancomycin resistance carrying Tn1549: enzymatic requirements and target site preferencesMolecular microbiology
accessLevelPublic
2018 48 11
Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineeringNucleic acids research
accessLevelPublic
2018 79 12
Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic ResistanceCell
accessLevelPublic
2018 93 21
Effects of stably incorporated iron on protein phosphatase‐1 structure and activityFEBS letters
accessLevelPublic
2018 60 27
Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone HfqScientific reports
accessLevelPublic
2017 52 22
Structural Determinants of Sleeping Beauty Transposase ActivityMolecular therapy
accessLevelPublic
2016 62 7
Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineeringNature communications
accessLevelPublic
2016 64 32
Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bendingeLife
accessLevelPublic
2016 71 15
An integrated approach for genome annotation of the eukaryotic thermophile Chaetomium thermophilumNucleic Acids Research
accessLevelPublic
2014 167 89
Structure of an Escherichia coli Hfq:RNA complex at 0.97 Å resolutionActa crystallographica. Section F, Structural biology communications
accessLevelRestricted
2014 49 0
Catalytic mechanism of α-phosphate attack in dUTPase is revealed by X-ray crystallographic snapshots of distinct intermediates, 31P-NMR spectroscopy and reaction path modellingNucleic acids research
accessLevelPublic
2013 62 16
Acquisition of an Archaea-like ribonuclease H domain by plant L1 retrotransposons supports modular evolutionProceedings of the National Academy of Sciences of the United States of America
accessLevelRestricted
2013 35 0
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