Episodic future thinking in autism spectrum disorder and 22q11.2 deletion syndrome: association with anticipatory pleasure and social functioning

Article Article scientifique Article Episodic future thinking in autism spectrum disorder and 22q11.2 deletion syndrome: association with anticipatory pleasure and social functioning eng 2021 author Feller Clémence 847302 author Dubois Charlotte 933238 author Eliez Stéphan 39336 author Schneider Maude 594384 4587-4604 10.1007/s10803-021-04903-2 33586083 0162-3257 http://link.springer.com/10.1007/s10803-021-04903-2 Episodic future thinking (EFT) has been suggested to underlie anticipatory pleasure (AP), itself known to play a crucial role in social functioning (SF). Both AP and SF are impaired in various clinical populations, including autism spectrum disorders (ASD) and 22q11.2 deletion syndrome (22q11DS). Therefore, the relationship between EFT, AP and SF was investigated, as well as the potential role of projecting oneself in a social vs. non-social context. Seventy-seven participants [24 with 22q11DS, 20 with ASD, 33 typically developing controls (TDs)] (aged 12–25) were included. They were assessed with a future thinking task in which they were asked to recall a memory and produce a likely event. Narratives were rated based of specificity, richness and imaginability. Participants completed questionnaires assessing AP and SF. Narratives from ASD and 22q11DS participants were rated as less vivid compared to TDs. However, the characteristics of the narratives differed between ASD and 22q11DS participants in terms of specificity and level of details, as well as in reaction to social condition. Moreover, correlations were found between AP and EFT in both ASD and 22q11DS participants, and between SF and EFT in ASD participants. These results point towards impairments in EFT in both ASD and 22q11DS participants but with a specific profile in each condition. The observed associations between EFT and AP suggest that decreased autonoetic consciousness might underlie AP impairments. In ASD individuals, the association between SF and EFT highlights the need to better characterize EFT since EFT could be another mechanism contributing to social difficulties. Episodic future thinking Autism spectrum disorder 22q11.2 deletion syndrome Anticipatory pleasure Social functioning Autonoetic consciousness Dewey 150 Dewey 576.5 Dewey 616.89 Swiss National Science Foundation Towards an embodied and ecological understanding of social impairments in neurodevelopmental disorders PZ00P1_174206 CH Careers 135 Département de médecine génétique et développement 21D 60 Département de psychiatrie 225 108 Section de psychologie 71 false 421 Laboratoire d'imagerie et de psychopathologie développementale 693 1302 Unité de psychologie clinique des situations de handicap https://doi.org/10.26037/yareta:cyluachonne73ijg6udtmfm44a Journal of Autism and Developmental Disorders 51 4f8efee3-6340-459b-b6b0-b49e419e1db6 Article (Published version) Public Feller2021_Article_EpisodicFutureThinkingInAutism-1.pdf 865586 application/pdf CC BY 5db343b9-d3e9-4182-87ca-4a24f412f39b Appendix Public 10803_2021_4903_MOESM1_ESM.docx 13851 application/vnd.openxmlformats-officedocument.wordprocessingml.document openAccess Faculté de médecine / Section de médecine fondamentale / Département de médecine génétique et développement Faculté de médecine / Section de médecine clinique / Département de psychiatrie Faculté de psychologie et des sciences de l'éducation / Section de psychologie

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Episodic future thinking in autism spectrum disorder and 22q11.2 deletion syndrome: association with anticipatory pleasure and social functioning	Journal of Autism and Developmental Disorders			2021	319	352

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Dubois, Charlotte