Enterovirus D: a small but versatile species

Article Article scientifique Revue de la littérature Enterovirus D: a small but versatile species eng 2021-08-17 2021-08-17 author Cordeiro Filipe Inès 0000-0001-6052-3506 884452 author Da Rocha Soares Guedes Mariana 0000-0002-5549-0620 930971 author Zdobnov Evgeny 636914 author Tapparel Caroline 0000-0002-0411-6567 27039 1758 10.3390/microorganisms9081758 34442837 2076-2607 PMC8400195 Enteroviruses (EVs) from the D species are the causative agents of a diverse range of infectious diseases in spite of comprising only five known members. This small clade has a diverse host range and tissue tropism. It contains types infecting non-human primates and/or humans, and for the latter, they preferentially infect the eye, respiratory tract, gastrointestinal tract, and nervous system. Although several <i>Enterovirus D</i> members, in particular EV-D68, have been associated with neurological complications, including acute myelitis, there is currently no effective treatment or vaccine against any of them. This review highlights the peculiarities of this viral species, focusing on genome organization, functional elements, receptor usage, and pathogenesis. EV-D111 EV-D120 EV-D68 EV-D70 EV-D94 Enterovirus Enterovirus D Picornavirus Dewey 616 Dewey 576.5 Swiss National Science Foundation Factors modulating rhinovirus and enterovirus pathogenicity 310030_184777 CH Project funding European Commission Organoids for Virus Research - An innovative training-ETN programme 812673 OrganoVIR EU H2020 54 Département de microbiologie et médecine moléculaire 21B 135 Département de médecine génétique et développement 21D false 931 Identification des facteurs clés impliqués dans la pathogénèse des rhinovirus et entérovirus 953 493 Génomique Evolutionnaire Computationnelle 830 Microorganisms 9 8 5559ca80-d361-4bfe-aee8-d95b284b58af Article (Published version) Public Article-scientifique-from-europePmc.pdf 2020370 application/pdf CC BY-4.0 4959d5c9-9bde-4ead-aa8b-48574de49222 Supplemental data Public microorganisms-1325600-supplementar.pdf 614113 application/pdf CC BY-4.0 openAccess Faculté de médecine / Section de médecine fondamentale / Département de microbiologie et médecine moléculaire Faculté de médecine / Section de médecine fondamentale / Département de médecine génétique et développement

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Enterovirus D: a small but versatile species	Microorganisms			2021	195	175

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Da Rocha Soares Guedes, Mariana