Clot composition and pre-interventional radiological characterization for better prognosis and potential choice of treatment in acute ischemic strokes

Article Article scientifique Revue de la littérature Clot composition and pre-interventional radiological characterization for better prognosis and potential choice of treatment in acute ischemic strokes eng 2025-03-10 2025-03-10 author Gurary Samuel Tell 0009-0003-6877-8337 927903 author Dumitriu Lagrange Daniela 916457 author Botta Daniele 417457 author Machi Paolo 860889 Département de radiologie et informatique médicale (RADIO) author Wanke Isabel author Kurz Félix Tobias 0000-0001-7616-7147 419472 Département de radiologie et informatique médicale (RADIO) author Lövblad Karl-Olof 0000-0003-2768-9779 135154 Département de radiologie et informatique médicale (RADIO) 17 10.3390/ctn9010017 2514-183X https://www.mdpi.com/2514-183X/9/1/17 <p>Acute ischemic stroke (AIS) remains a critical concern in clinical practice, with significant implications for patient outcomes and healthcare costs. This review highlights the role of clot composition in AIS, emphasizing the clinical relevance of radiological characterization. Variations in thrombus composition, such as red blood cell (RBC)-rich and white blood cell (WBC)-dominant clots, influence the success of thrombolytic therapies and mechanical thrombectomy. Advanced radiological techniques, including non-contrast CT, CT angiography, and MRI, are essential for pre-interventional clot characterization, guiding optimal treatment decisions. Integrating artificial intelligence (AI) in radiology can enhance the precision of clot composition assessment, facilitating personalized treatment approaches and improving predictive accuracy. By combining histopathological insights with imaging and AI technologies, this review underscores the importance of comprehensive radiological evaluation in the management of AIS, ultimately aiming to enhance clinical outcomes and reduce the burden on healthcare systems.</p> Stroke Clot Computed tomography Magnetic resonance tomography Thrombectomy Dewey 616.0757 Swiss National Science Foundation Characterizing the intravascular clot in acute stroke with multi-parametric imaging 182382 CH Projects 62 Département de radiologie et informatique médicale 227 false 470 Ischémie cérébrale et connectivité 801 1470 Laboratoire de neuroimagerie quantitative et computationnelle 1078 Clinical and translational neuroscience 9 1 7059a1d2-61e9-451a-8cbb-8d1665b63bee Article (Published version) Public Article_scientifique_from_crossref.pdf 295914 application/pdf CC BY-4.0 8eb2dcb60591e757ad7f7ed582becaf45a800191419ed4014fe81cc0554a547a openAccess Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

Title	Published in	Year	Views	Downloads

Clot composition and pre-interventional radiological characterization for better prognosis and potential choice of treatment in acute ischemic strokes	Clinical and translational neuroscience	2025	80	308
Clot composition and Radiological Characterization in the setting of acute Ischemic Stroke		2025	11	0

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Gurary, Samuel Tell