A novel test for hyposalivation using a sugar cube

Article Article scientifique Article A novel test for hyposalivation using a sugar cube eng 2024-04-29 2024-08 author Spyraki Foteini 0000-0003-4980-5013 Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland. 926208 CUMD - Clinique de gérodontologie et prothèse adjointe (CGPA) author Maniewicz Wins Sabrina 0000-0002-3343-787X Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland. 697227 CUMD - Clinique de gérodontologie et prothèse adjointe (CGPA) author Mojon Philippe 0000-0001-7861-2494 Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland.,Division of Fixed Prosthodontics and Biomaterials, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland. 26576 author Muller Frauke 0000-0003-3981-0134 Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, University of Geneva, Geneva, Switzerland.,Division of Geriatrics, Department of Rehabilitation and Geriatrics, University Hospitals of Geneva, Thônex, Switzerland. 135177 CUMD - Division de gérodontologie et prothèse adjointe - communs (DGPA) 1433-1439 10.1111/joor.13715 38685706 0305-182X https://onlinelibrary.wiley.com/doi/10.1111/joor.13715 Background: Hyposalivation is a highly prevalent condition in old persons. Objectives: The aim of this study was to assess a novel tool for the diagnosis of hyposalivation using a sugar cube and to compare its reliability to other validated test methods. Methods: Five tests were performed: unstimulated salivary flow test by draining method (USFT), oral moisture device Mucus® (MCS), sugar cube test (SCT), stimulated salivary flow test by chewing gum (CG) and Saxon test (SX). The sugar cube test consisted in measuring the time needed to disintegrate a standard-sized sugar cube N°4 (5.6 g) placed beneath the tongue. Bivariate correlation analyses were performed. ROC curve analysis and the Youden Index were used to determine the cut-off value. Sensitivity and specificity were calculated according to the determined cut-off point. Results: A total of 121 participants were recruited, with an average age of 49.8 ± 18.2 years. The USFT was best correlated with the SCT. No correlation was found between SCT and the stimulated saliva tests (CG, SX) as well as the MCS test. According to the Youden index, 140 s is appropriate to diagnose hyposalivation. Sensitivity of .64 and specificity of .91 were found for SCT using USFT as gold standard. The mean subjective evaluation score of the SCT was 3.1 ± 1, significantly higher than USFT 2.6 ± 1.1 (p < .05). Conclusions: The sugar cube test proved to be a useful method for assessing unstimulated salivation, reducing test execution time and causing less participant discomfort than the gold standard unstimulated salivary flow test. Oral hyposalivation Salivary flow rate Sugar cube Testing method Xerostomia Humans Xerostomia / diagnosis Xerostomia / physiopathology Female Middle Aged Male Reproducibility of Results Saliva / chemistry Adult Sensitivity and Specificity Aged Chewing Gum Salivation / physiology Sugars / analysis ROC Curve Dewey 617.6 Dewey 618.97 212 Division de gérodontologie et prothèse adjointe 24Q3 210 Division de prothèse fixe et biomatériaux 24Q2 65 Département de réadaptation et gériatrie 22B false 467 Groupe de recherche Frauke Müller 797 188 Groupe Kiliaridis Stavros (médecine dentaire) 239 Journal of oral rehabilitation 51 8 5a86f278-1186-49ba-9064-a3c56974c6a7 Article (Published version) Public J_of_Oral_Rehabilitation_-_2024_-_S.pdf 715883 application/pdf CC BY-NC-4.0 c5d95a3a6c111e35f9bbb4ab6aefa118edf26903019fdd9bec723705aa234fbe openAccess Faculté de médecine / Section de médecine dentaire / Département de réhabilitation oro-faciale / Division de gérodontologie et prothèse adjointe Faculté de médecine / Section de médecine dentaire / Département de réhabilitation oro-faciale / Division de prothèse fixe et biomatériaux Faculté de médecine / Section de médecine clinique / Département de réadaptation et gériatrie

Title	Published in	Year	Views	Downloads

Xérostomie et hyposalivation : Facteurs de risque liés au patient		2025	32	411
A novel test for hyposalivation using a sugar cube	Journal of oral rehabilitation	2024	88	172

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