Impact of a music intervention on heart rate variability in very preterm infants

Article Article scientifique Article Impact of a music intervention on heart rate variability in very preterm infants eng 2024-11-19 2025-05 author Barcos Munoz Francisca Mariana 0000-0001-7143-6117 Neonatal Intensive Care Unit, University Hospital of Geneva, Geneva, Switzerland. 871644 Francisca Barcos Munoz author Hernández Alfredo I Rennes University Hospital, Inserm, Rennes, France. author De Araujo Abreu Adelaïde Marlène Neonatal Intensive Care Unit, University Hospital of Geneva, Geneva, Switzerland. 895501 author Fau Sébastien Neonatal Intensive Care Unit, University Hospital of Geneva, Geneva, Switzerland. 833792 author Filippa Manuela 0000-0002-1310-8008 Swiss Center of Affective Sciences, Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland.,Division of Development and Growth, Child and Adolescent Department, University of Geneva, Geneva, Switzerland. 890536 Section de psychologie (PSICO) author Hüppi Petra Susan Division of Development and Growth, Child and Adolescent Department, University of Geneva, Geneva, Switzerland. 133591 Département de Pédiatrie, Gynécologie et Obstétrique (PETRI) author Beuchée Alain Rennes University Hospital, Inserm, Rennes, France. author Baud Olivier Neonatal Intensive Care Unit, University Hospital of Geneva, Geneva, Switzerland.,Inserm U1141, University Paris-Cité, Paris, France.,Department of Neonatal Medicine, Cochin-Port Royal Hospital, FHU PREMA, AP-HP Centre, Paris, France. 850348 886-893 10.1111/apa.17500 39560313 0803-5253 https://onlinelibrary.wiley.com/doi/10.1111/apa.17500 Aim: Infants born very preterm spend their early postnatal life in a neonatal intensive care unit, where irregular and unpredictable sounds replace the structured and familiar intrauterine auditory environment. Music interventions may contribute to alleviate these deleterious effects by reducing stress and providing a form of environmental enrichment. Material and methods: This was an ancillary study as part of a blinded randomised controlled clinical trial entitled the effect of music on preterm infant's brain development. It measured the impact of music listening on the autonomic nervous system (ANS), we assessed heart rate variability (HRV) through high-resolution recordings of heart rate monitoring, at three specific postmenstrual ages in premature infants. Results: From 29 included subjects, 18 were assessed for complete HRV dataset, including nine assigned to the music intervention and nine to the control group. Postmenstrual age appeared to be the main factor influencing HRV from 33 weeks to term equivalent age. Further analyses did not reveal any detectable effect of music intervention on ANS response. Conclusion: This study found that ANS responses were not modified by recorded music intervention in very preterm infants during wakefulness or sleep onset. Further research is warranted to explore other factors influencing ANS development in this population. Autonomic nervous system Heart rate variability Music intervention Neonatal intensive care unit Preterm infants Dewey 150 Dewey 618 108 Section de psychologie 71 58 Département de pédiatrie, gynécologie et obstétrique 223 false 594 Neuroscience de l'émotion et dynamiques affectives (NEAD) 1241 Affective sciences 150 L'imagerie cérébrale 184 Acta pædiatrica 114 5 55e293fe-252a-408b-a159-7ee8a92392a9 Article (Published version) Restricted file.pdf 610614 application/pdf fe8d18af3035a4457cc795949e0d051e951d7b28b4c3104879697cff9c04c294 7a001b9b-cd8e-4f3c-843e-9fe87b698851 Article (Accepted version) Public Paper-0900-English-Editor-031024_Ma.pdf 248292 application/pdf Restricted 2025-11-20 d9612d5fd5445c1d978f1cbfad46cd85a357e00068f2b3907ae449c0aaba89b7 b6a236ee-848a-4fd1-ba28-f86be256dba0 Appendix Restricted apa17500-sup-0002-tables1.docx 14304 application/vnd.openxmlformats-officedocument.wordprocessingml.document ee8bb6bf71d83581e26ddee963c7370172fdd92e506c4f6662790c60d44c1aa8 28838e31-639e-467f-9455-e06712470eba Appendix Restricted apa17500-sup-0001-appendixs1.pdf 1189630 application/pdf 646758991085fef7e6a5cc85c08586ec1381ddb8bb9e080e85e669aaa78a64b8 9c24cc17-fa71-4be7-919b-5920bef3062c Appendix Restricted Table_1_and_2.xlsx 12965 application/vnd.openxmlformats-officedocument.spreadsheetml.sheet Table 1 and 2 2d6134a46242ae749f9c841b9c3b20f6fdda956245060224d5e02b9f6a71bdf9 673ea14f-29c2-4407-b1f4-b07c677666d6 Appendix Restricted Flow_chart_english.docx 41922 application/vnd.openxmlformats-officedocument.wordprocessingml.document Flow chart in English 94d4357ee9678a3474c048148d2620746220eb3f95316245257b61473803a60c openAccess Faculté de psychologie et des sciences de l'éducation / Section de psychologie Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique

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Impact of a music intervention on heart rate variability in very preterm infants	Acta pædiatrica			2024	118	138

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De Araujo Abreu, Adelaïde Marlène