The Unseen Burden : Uncovering Shame in Parkinson’s Disease

Article Article scientifique Article The Unseen Burden : Uncovering Shame in Parkinson’s Disease eng 2025-05-19 2025-10 author Catalano Sabina 507782 author Benis Damien 830490 Département de Pédiatrie, Gynécologie et Obstétrique (PETRI) author Rime Charline Lara Aurélia 878865 Département des neurosciences cliniques (OTONO) author Forjaz MJ author Krack Paul author Rodriguez-Blazquez Carmen author Fleury Vanessa 840771 Département des neurosciences cliniques (OTONO) 1551-1559 10.1002/mdc3.70128 40384367 2330-1619 PMC12528978 https://movementdisorders.onlinelibrary.wiley.com/doi/10.1002/mdc3.70128 Background: Shame is frequent in Parkinson’s disease (PD) and often overlooked. Objective: TheaimwastoassessfactorsassociatedwithPD-relatedshame. Methods: PD-relatedshamewasmeasuredusingtheShameandEmbarrassmentinPD(SPARK)scaleinpatients without cognitive impairment. Correlation between personal determinants (demographics, psychological traits [shame/guilt propensity, trait anxiety]), PD-related determinants (PD characteristics; motor, cognitive, and neuropsychiatric symptoms; medication; and health-related quality of life [QoL]), and SPARK was analyzed using multiple correlation analysis and generalized linear mixed models. To describe the cohort’s response to shame, data- driven clustering based on SPARK was conducted, and clusters’ associations with the determinants were analyzed. Results: Forty-sevenPDpatientswereincluded.PD-relatedshamecorrelatedwithpsychologicaltraits(trait anxiety, shame, and guilt propensity), clinical symptoms (dyskinesia, state anxiety, depression, and apathy), and QoL. These determinants explained 79.3% of the total variance in the subsequent linear model analysis, with QoL and anxiety as the strongest covariates of shame. Apathy positively covaried with SPARK self-esteem subscale. Cluster analysis identified 3 patient groups. Highest-intensity shame cluster demonstrated elevated scores on both motor and nonmotor symptom–related shame and was associated with higher levels in anxiety, depression, and apathy, and poorer QoL. The remaining clusters showed a dissociation, with motor symptom– related shame predominating in one and nonmotor symptom–related shame in the other. Conclusions: Thisstudyprovidesanin-depthunderstandingofshame,highlightingitsmultifactorialnature.Due to its impact on QoL, shame should be addressed in clinical practice through pharmacological/ nonpharmacological interventions, targeting both shame and its modifiable determinants. Identifying distinct shame profiles underscores the need for tailored interventions. Parkinson's disease Embarrassment Health‐related quality of life Shame Stigma Dewey 128.37 Dewey 616.8 Dewey 150 61 Département des neurosciences cliniques 226 108 Section de psychologie 71 15 Centre interfacultaire en sciences affectives 0D8 false Movement disorders clinical practice 12 10 3b6e7260-f639-41bd-a872-98e01c3fb448 Article (Published version) Public Catalano_2025.pdf 394895 application/pdf CC BY-4.0 c33cb7d1578fe09be9c0560383fe66b9b70a72409a09a6366b6e198688f6679a bb6efb8d-430f-4af0-8b3d-a73879ed776d Supplemental data Public mdc370128-sup-0001-supinfo.docx 602353 application/vnd.openxmlformats-officedocument.wordprocessingml.document b67c6bb0e2e82b195b4e5c2c080b2316757bed5180f948173ddf46089a56e9e7 openAccess Faculté de médecine / Section de médecine clinique / Département des neurosciences cliniques Faculté de psychologie et des sciences de l'éducation / Section de psychologie Centres et instituts / Centre interfacultaire en sciences affectives

Title	Published in	Year	Views	Downloads

The Unseen Burden : Uncovering Shame in Parkinson’s Disease	Movement disorders clinical practice	2025	14	21
Valence émotionnelle et Projection dans le futur ; Exploration du lien avec l’alexithymie et les stratégies de coping chez les adolescents et les jeunes adultes avec un trouble du spectre de l’autisme		2024	78	4

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