Immunotoxicological risk assessment of As, Cd, Hg, Pb and essential metals

Diplôme Master d'études avancées Immunotoxicological risk assessment of As, Cd, Hg, Pb and essential metals eng 2018-07-16 author Zwingenberger Kai 868256 director Aicher Lothar 961415 This is a review of immunotoxicological effects of arsenic, cadmium, mercury and lead with a view to the balance of interactions between metallic toxicants and the essential metals copper, selenium and zinc. Working hypothesis at the outset was that, singly and combined, metals predictably impact the human immune system and that resulting risk could be quantitated. A tentative objective was to prototype an adverse outcome pathway for one or more metals centered upon a key event in regulatory T-cell differentiation. Such an adverse outcome would be over- or underperformance, i.e. immunosuppression or autoimmunity. Dewey 610 Dewey 615 Master of Advanced Studies in Toxicology 3 Faculté de médecine 2 31 Section des sciences pharmaceutiques 17 false b2c11873-5d2e-42c3-9d8d-a9e0e98d4650 Master thesis Restricted MAS_Toxicology_KaiZwingenberger.pdf 889578 application/pdf restrictedAccess Faculté de médecine Faculté des sciences / Section des sciences pharmaceutiques

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Immunotoxicological risk assessment of As, Cd, Hg, Pb and essential metals				2018	92	3

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Zwingenberger, Kai