Development of the Thin TOF-PET scanner based on fast timing monolithic silicon pixel sensors

Diplôme Thèse Development of the Thin TOF-PET scanner based on fast timing monolithic silicon pixel sensors eng 2020-01-29 author Hayakawa Daiki 850200 director Iacobucci Giuseppe 752364 director Ratib Osman 28848 10.13097/archive-ouverte/unige:131202 urn:nbn:ch:unige-1312028 Sc. 5433 The Thin-TOF PET (TT-PET) project aims at the construction of a small-animal PET scanner based on monolithic silicon pixel sensors. The iterative image reconstruction was developed using a maximum a posteriori probability estimation algorithm. Reconstructed images from Monte-Carlo data show high signal-to-noise ratio with unprecedented spatial resolution. The detector ASICs were designed with the support of a Technology CAD simulation framework. A measurement setup based on a 22Na radioactive source showed that the single layer detection efficiency of the demonstrator chip is approximately 0.19%, which is in good agreement with the simulations. The same setup was used to measure the time resolution, that resulted to be 70ps (RMS). This result, although excellent for a silicon sensor, is a factor two below the specification of the TT-PET project. It is created by a systematic error in the measurement of the charge that will be corrected in future chips. Dewey 500.2 Dewey 616.0757 Swiss National Science Foundation TT-PET: Thin Time-of-Flight PET with depth of interaction measurement capability based on very-low noise Silicon-Germanium BJT electronics and semiconductor detector 160808 CH Programmes 34 Département de physique nucléaire et corpusculaire 132 62 Département de radiologie et informatique médicale 227 false fca655f5-ef74-4801-ae44-5aaceb876b84 Thesis Public DoctoralThesis_daikihayakawa.pdf 33735044 application/pdf openAccess Faculté des sciences / Section de physique / Département de physique nucléaire et corpusculaire Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

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Development of the Thin TOF-PET scanner based on fast timing monolithic silicon pixel sensors				2020	748	106

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Hayakawa, Daiki