Sexual Identity Disorder and Psychosis in Klinefelter Syndrome: A Synthesis of Literature and a Case Report

Article Article scientifique Revue de la littérature Sexual Identity Disorder and Psychosis in Klinefelter Syndrome: A Synthesis of Literature and a Case Report eng 2019-02 author Maillefer Aude 818117 author Sabe Michel 889218 author Coste Christophe 848620 author Bartolomei Javier 84288 author Jaafar Jaafar 843685 author Sentissi El Idrissi Othman 0000-0001-6280-2197 711790 121-125 10.1097/NMD.0000000000000930 30672880 0022-3018 https://journals.lww.com/jonmd/Fulltext/2019/02000/Sexual_Identity_Disorder_and_Psychosis_in.10.aspx Klinefelter syndrome (KS) 47, XXY is the most frequent chromosomal abnormality causing hypogonadism in humans. This chromosomal abnormality of number in its classical form called homogeneous (supernumerary X) is generally the result of a meiosis accident. Several studies have suggested that individuals with KS are at greater risk of developing various psychiatric disorders, including depression and schizophrenia. The diagnosis is made based on subnormal testosterone with high pituitary gonadotropins and confirmed by determining the karyotype on a blood simple. We did a literature review using an electronic search in three databases: Pubmed/MEDLINE, Google Scholar, and PsychInfo. We found that since 1989, seven case reports with KS and mental disorders with similar and different characteristics of our case illustration of a patient with KS and psychosis were published. Gender Dysphoria / etiology Humans Klinefelter Syndrome / complications Male Middle Aged Psychotic Disorders / etiology Dewey 616.89 Dewey 616 60 Département de psychiatrie 225 56 Département de médecine 221 false The journal of nervous and mental disease 207 2 f1b8c3f9-d0c6-41ec-8408-8e4d7f517bd6 Article (Published version) Restricted Sexual_Identity_Disorder_and_Psycho.pdf 246400 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département de psychiatrie Faculté de médecine / Section de médecine clinique / Département de médecine

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Sexual Identity Disorder and Psychosis in Klinefelter Syndrome: A Synthesis of Literature and a Case Report	The journal of nervous and mental disease			2019	277	0

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Coste, Christophe