Do patients with different craniofacial patterns have differences in upper airway volume ? A systematic review with network meta-analysis

Article Article scientifique Méta-analyse Do patients with different craniofacial patterns have differences in upper airway volume ? A systematic review with network meta-analysis eng 2024-04-01 author Altheer Charlotte Madeleine Division of Orthodontics, University Clinics of Dental Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland. 835580 author Papageorgiou Spyridon N 0000-0003-1968-3326 Clinic of Orthodontics and Pediatric Dentistry, Center for Dental Medicine, University Zurich, Zurich, Switzerland. author Antonarakis Gregory 0000-0001-6741-6922 Division of Orthodontics, University Clinics of Dental Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland. 133276 CUMD - Division d'orthodontie - communs (DORT) author Papadopoulou Alexandra 0000-0001-5981-0479 Division of Orthodontics, University Clinics of Dental Medicine, Faculty of Medicine, University of Geneva, Geneva, Switzerland.,Discipline of Orthodontics, Sydney Dental School, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia. 974834 CUMD - Clinique d'orthodontie (CORT) cjae010 10.1093/ejo/cjae010 38526866 0141-5387 PMC10962399 https://academic.oup.com/ejo/article/46/2/cjae010/7634571 Background: Craniofacial skeletal discrepancies have been associated with upper airway dimensions. Objective: To identify differences in upper airway volume across different sagittal and vertical skeletal patterns. Search methods: Unrestricted literature searches in eight databases/registers for human studies until May 2023. Selection criteria: Cross-sectional studies measuring upper airway volumes using three-dimensional imaging in healthy patients of different sagittal (Class I, Class II, and Class III) or vertical (normodivergent, hypodivergent, and hyperdivergent) craniofacial morphology. Data collection and analysis: Duplicate independent study selection, data extraction, and risk of bias assessment. Random-effects frequentist network meta-analysis was performed followed by subgroup-analyses and assessment of the quality of clinical recommendations (confidence in effect estimates) with the CINeMA (Confidence in Network Meta-Analysis) approach. Results: Seventy publications pertaining to 66 unique studies were included with 56 studies (5734 patients) contributing to meta-analyses. Statistically significant differences were found for total pharyngeal airway volume, with Class II having decreased airway volume (-2256.06 mm3; 95% Confidence Interval [CI] -3201.61 to -1310.51 mm3) and Class III increased airway volume (1098.93 mm3; 95% CI 25.41 to 2172.45 mm3) compared to Class I. Significant airway volume reductions for Class II were localized mostly at the oropharynx, followed by the palatopharynx, and the glossopharynx. Significant airway volume increases for Class III were localized mostly at the oropharynx, followed by the intraoral cavity, and hypopharynx. Statistically significant differences according to vertical skeletal configuration were seen only for the oropharynx, where hyperdivergent patients had reduced volumes compared to normodivergent patients (-1716.77 mm3; 95% CI -3296.42 to -137.12 mm3). Airway differences for Class II and Class III configurations (compared to Class I) were more pronounced in adults than in children and the confidence for all estimates was very low according to CINeMA. Conclusions: Considerable differences in upper airway volume were found between sagittal and vertical skeletal configurations. However, results should be interpreted with caution due to the high risk of bias, owing to the retrospective study design, inconsistencies in anatomic compartment boundaries used, samples of mixed children-adult patients, and incomplete reporting. Clinical trial registration: PROSPERO (CRD42022366928). Adult Child Imaging Three-dimensional Oropharynx Hypopharynx Airway structure Airways Pharyngeal Upper respiratory tract Network meta-analysis Airway device Dewey 617.6 209 Division d'orthodontie 24Q1 false 188 Groupe Kiliaridis Stavros (médecine dentaire) 239 1448 Orthodontie 1065 https://zenodo.org/records/10042588 European journal of orthodontics 46 2 818b2207-d59c-4e38-9d34-0c04d86e9503 Article (Published version) Public Article_scientifique_from_unpaywall.pdf 1761474 application/pdf CC BY-4.0 ef22a14d8c5cd4fa62a21c68bb419907e5a09589f965a9db129a5b0b60c32332 bc53f79c-2bfc-410f-b37a-715e6f48071d Supplemental data Public cjae010_suppl_supplementary_tables_.docx 874420 application/vnd.openxmlformats-officedocument.wordprocessingml.document 303d3daf3f948619735a35443fa7c60b07536063c3efce7e17881b89b5809c06 c72f9c40-e81e-4e84-a34e-cdae650a9cd2 Supplemental data Public cjae010_suppl_supplementary_tables_1.docx 507376 application/vnd.openxmlformats-officedocument.wordprocessingml.document 13ebdb4cdce1b8daccb113cca8bc219e2b4e3720eeab8caa070e168e5d516341 openAccess Faculté de médecine / Section de médecine dentaire / Département de réhabilitation oro-faciale / Division d'orthodontie

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Do patients with different craniofacial patterns have differences in upper airway volume ? A systematic review with network meta-analysis	European journal of orthodontics			2024	70	280

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Altheer, Charlotte Madeleine