Two cases of highly concentrated hydrogen peroxide poisoning with portal venous gas treated using hyperbaric oxygen therapy

Article Article scientifique Rapport de cas Two cases of highly concentrated hydrogen peroxide poisoning with portal venous gas treated using hyperbaric oxygen therapy eng 2025-02-08 2025-02 author Vallelian Marie 821867 author Juillerat André 671488 author Sunic Matea author Schneider Claudio author Boet Sylvain 0000-0002-1679-818X 413164 Département d'anesthésiologie, pharmacologie et soins intensifs (APSIC) e261916 10.1136/bcr-2024-261916 39922573 1757-790X PMC12034919 https://casereports.bmj.com/lookup/doi/10.1136/bcr-2024-261916 <p>Hydrogen peroxide poisoning is a rare but potentially severe poisoning that can cause digestive tract irritation and/or gas embolism when ingested. The clinical presentation varies from asymptomatic patients to severe embolic consequences or even death. There is little evidence on the treatment of such poisoning to guide physicians in caring for these patients. This paper reports on two cases of highly concentrated hydrogen peroxide poisoning after accidental ingestion. Both patients showed evidence of portal venous gas, with one patient exhibiting significant symptoms while the other did not. Both were treated with hyperbaric oxygen therapy (HBOT), with a follow-up CT scan revealing a complete resolution of the portal venous gas. This suggests that HBOT is effective for both symptomatic and asymptomatic patients with portal venous gas and should be considered as an effective treatment option in cases of highly concentrated hydrogen peroxide poisoning.</p> Adult Embolism, Air / chemically induced Embolism, Air / diagnostic imaging Embolism, Air / etiology Embolism, Air / therapy Female Humans Hydrogen Peroxide / poisoning Hyperbaric Oxygenation / methods Male Middle Aged Portal Vein / diagnostic imaging Tomography, X-Ray Computed Treatment Outcome Dewey 616 Dewey 617 63 Département d'anesthésiologie, pharmacologie, soins intensifs et urgences 229 56 Département de médecine 221 false BMJ case reports 18 2 b9d7ee63-ed14-42e0-9883-8e649d7441e6 Article (Published version) Public e261916.full.pdf 722244 application/pdf CC BY-NC-4.0 477bd207622ada677c5e157b14126a7fdde72ec83f3743743b8fadc733f1218d openAccess Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences Faculté de médecine / Section de médecine clinique / Département de médecine

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Two cases of highly concentrated hydrogen peroxide poisoning with portal venous gas treated using hyperbaric oxygen therapy	BMJ case reports			2025	65	967

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Vallelian, Marie