Randomized controlled trials of non-pharmacological interventions for healthy seniors: Effects on cognitive decline, brain plasticity and activities of daily living-A 23-year scoping review

Article Article scientifique Revue de la littérature Randomized controlled trials of non-pharmacological interventions for healthy seniors: Effects on cognitive decline, brain plasticity and activities of daily living-A 23-year scoping review eng 2024-02-24 2024-05-15 author James Clara 0000-0001-7480-0682 Geneva Musical Minds Lab (GEMMI Lab), Geneva School of Health Sciences, University of Applied Sciences and Arts Western Switzerland HES-SO, Avenue de Champel 47, 1206, Geneva, Switzerland.,Faculty of Psychology and Educational Sciences, University of Geneva, Boulevard Carl-Vogt 101, 1205, Geneva, Switzerland. 501487 Section de psychologie (PSICO) author Müller David Maxime Geneva Musical Minds Lab (GEMMI Lab), Geneva School of Health Sciences, University of Applied Sciences and Arts Western Switzerland HES-SO, Avenue de Champel 47, 1206, Geneva, Switzerland. 816786 author Mueller Cécile Armella Héléna Geneva Musical Minds Lab (GEMMI Lab), Geneva School of Health Sciences, University of Applied Sciences and Arts Western Switzerland HES-SO, Avenue de Champel 47, 1206, Geneva, Switzerland. 853546 author Van De Looij Yohan Geneva Musical Minds Lab (GEMMI Lab), Geneva School of Health Sciences, University of Applied Sciences and Arts Western Switzerland HES-SO, Avenue de Champel 47, 1206, Geneva, Switzerland.,Division of Child Development and Growth, Department of Pediatrics, School of Medicine, University of Geneva, 6 Rue Willy Donzé, 1205 Geneva, Switzerland.,Center for Biomedical Imaging (CIBM), Animal Imaging and Technology Section, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH F1 - Station 6, 1015, Lausanne, Switzerland. 652102 Département de Pédiatrie, Gynécologie et Obstétrique (PETRI) author Altenmüller E Hannover University of Music, Drama and Media, Institute for Music Physiology and Musicians' Medicine, Neues Haus 1, 30175, Hannover, Germany.,Center for Systems Neuroscience, Bünteweg 2, 30559, Hannover, Germany. author Kliegel Matthias Faculty of Psychology and Educational Sciences, University of Geneva, Boulevard Carl-Vogt 101, 1205, Geneva, Switzerland.,Center for the Interdisciplinary Study of Gerontology and Vulnerability, University of Geneva, Switzerland, Chemin de Pinchat 22, 1207, Carouge, Switzerland. 761733 Section de psychologie (PSICO) author Van De Ville Dimitri 0000-0002-2879-3861 Ecole polytechnique fédérale de Lausanne (EPFL), Neuro-X Institute, Campus Biotech, 1211 Geneva, Switzerland.,University of Geneva, Department of Radiology and Medical Informatics, Faculty of Medecine, Campus Biotech, 1211 Geneva, Switzerland. 638484 Département de radiologie et informatique médicale (RADIO) author Marie Damien 0000-0001-8199-8260 Geneva Musical Minds Lab (GEMMI Lab), Geneva School of Health Sciences, University of Applied Sciences and Arts Western Switzerland HES-SO, Avenue de Champel 47, 1206, Geneva, Switzerland.,CIBM Center for Biomedical Imaging, Cognitive and Affective Neuroimaging Section, University of Geneva, 1211, Geneva, Switzerland. 849720 Centre d'imagerie bio-médicale (CIBM) e26674 10.1016/j.heliyon.2024.e26674 38707392 2405-8440 PMC11066598 Little is known about the simultaneous effects of non-pharmacological interventions (NPI) on healthy older adults' behavior and brain plasticity, as measured by psychometric instruments and magnetic resonance imaging (MRI). The purpose of this scoping review was to compile an extensive list of randomized controlled trials published from January 1, 2000, to August 31, 2023, of NPI for mitigating and countervailing age-related physical and cognitive decline and associated cerebral degeneration in healthy elderly populations with a mean age of 55 and over. After inventorying the NPI that met our criteria, we divided them into six classes: single-domain cognitive, multi-domain cognitive, physical aerobic, physical non-aerobic, combined cognitive and physical aerobic, and combined cognitive and physical non-aerobic. The ultimate purpose of these NPI was to enhance individual autonomy and well-being by bolstering functional capacity that might transfer to activities of daily living. The insights from this study can be a starting point for new research and inform social, public health, and economic policies. The PRISMA extension for scoping reviews (PRISMA-ScR) checklist served as the framework for this scoping review, which includes 70 studies. Results indicate that medium- and long-term interventions combining non-aerobic physical exercise and multi-domain cognitive interventions best stimulate neuroplasticity and protect against age-related decline and that outcomes may transfer to activities of daily living. Activities of daily living Aerobic interventions Artistic interventions Brain plasticity Cognitive decline Cognitive interventions Healthy older adults Magnetic Resonance Imaging Non-aerobic interventions Non-pharmacological interventions Psychometrics Randomized controlled trials Dewey 150 Swiss National Science Foundation Train the brain with music: Brain Plasticity and cognitive benefits induced by musicalpractice in elderly people in Germany and Switzerland 170410 CH 108 Section de psychologie 71 false 594 Neuroscience de l'émotion et dynamiques affectives (NEAD) 552 Traitement d'images médicales 893 Heliyon 10 9 46fd5f37-d7c4-47a0-9be7-9dff4388206b Appendix Public mmc5.pdf 210125 application/pdf 54e1593dfbfde2bb4d00e6de03c0246bfb06b4affe319888d95ed023303900a8 b0bc3773-8b17-4512-be4f-41f38eb2b727 Appendix Public mmc3.pdf 656293 application/pdf b0000de00893926b691b1ec05861107f17fb72dd90b7cd6bbc169f5b7b8c2758 87739542-0418-4f34-88e8-6a07fac654f9 Appendix Public mmc1.pdf 261640 application/pdf b5d9020a061258de04dab1af772a2b671e068cdd661451b70a3c86d65cb4bb4b 2bda2c8a-a3cc-4982-9142-fefbd968f504 Appendix Public mmc4.pdf 162510 application/pdf f1af13151100e7c390124545788d293012e1432321fb81ce693410feee4ac140 f2a4879c-49ca-4ac7-8147-fed13fe2de66 Appendix Public mmc6.pdf 300493 application/pdf e79892786299cfd3372728ea6d43ddb027da7b1ca3906aef5e3fbfaf31820ab1 ca1b9e7b-150a-4e69-8bba-af22c0231a28 Appendix Public mmc2.pdf 199676 application/pdf ba78e13b6eae6988a6779ae5c8af86a27fac9811fca9ddec0413fedcfa2b5ff3 4e6f22b8-c699-455e-83db-ff6c73a3ae30 Article (Published version) Public Article-scientifique-from-europePmc.pdf 1718993 application/pdf CC BY-NC 689e72ce6e5c40e58186f57d2be88b0b4656dee6f638e54a8a43b81417e9032c openAccess Faculté de psychologie et des sciences de l'éducation / Section de psychologie

Title	Published in	Year	Views	Downloads

Randomized controlled trials of non-pharmacological interventions for healthy seniors: Effects on cognitive decline, brain plasticity and activities of daily living-A 23-year scoping review	Heliyon	2024	87	499
The impact of music practice on functional plasticity in 42 healthy elderly: effects on working memory networks as measured by fMRI		2022	124	4

Archive ouverte UNIGE

Müller, David Maxime