Hyperglycemia Interacts with Ischemia in a Synergistic Way on Wound Repair and Myofibroblast Differentiation

Article Article scientifique Article Hyperglycemia Interacts with Ischemia in a Synergistic Way on Wound Repair and Myofibroblast Differentiation eng 2015 author Tobalem Mickael 642417 author Lévigne Dominik 748833 Dominik André-Lévigne author Modarressi Ali author Atashi Fatemeh 699062 author Villard Frédéric 81050 author Hinz Boris 514150 author Pittet Cuenod Brigitte Maud 114581 e471 10.1097/GOX.0000000000000443 26301160 0032-1052 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527645/ Hyperglycemia is known to adversely affect the outcome of ischemic insults, but its interaction with ischemia has not been investigated in wound repair yet. In this study, we develop a new animal model allowing to investigate the interaction between hyperglycemia and ischemia during the wound repair process. We focus on myofibroblast differentiation, a key element of wound repair. Dewey 617 57 Département de chirurgie 222 false 72 Groupe Pittet Cuenod Brigitte (chirurgie plastique et reconstructive) 96 Plastic and reconstructive surgery 3 7 b3ef5941-a3e1-4bcf-ad65-94cdc9cd69c3 Article (Published version) Public gox-3-e471.pdf 1075762 application/pdf openAccess Faculté de médecine / Section de médecine clinique / Département de chirurgie

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Hyperglycemia Interacts with Ischemia in a Synergistic Way on Wound Repair and Myofibroblast Differentiation	Plastic and reconstructive surgery			2015	538	229

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Villard, Frédéric