Development and Preliminary Validation of LoAD Calc, a Mobile App for Calculating the Maximum Safe Single Dose of Local Anesthetics

Article Article scientifique Article Development and Preliminary Validation of LoAD Calc, a Mobile App for Calculating the Maximum Safe Single Dose of Local Anesthetics eng 2021-06-25 2021-06-25 author Suppan Mélanie 0000-0002-8807-9619 526789 author Beckmann Tal Sarah author Gercekci Cenan 0000-0002-8296-3809 779460 author Sigrist Thérèse author Savoldelli Georges Louis 0000-0002-8968-6920 41344 author Fournier Roxane 33773 author Samer Caroline Flora 105661 799 10.3390/healthcare9070799 34202140 2227-9032 PMC8303623 https://www.mdpi.com/2227-9032/9/7/799 Local anesthetics systemic toxicity can lead to life-threatening situations. Correct calculation of the maximum safe dose is therefore paramount in preventing such complications. Different solutions have already emerged to support anesthesiologists but are seldom used in clinical practice as they require either access to a computer or specific documents to be at hand. A mobile app could provide an easy and practical solution; however, the few apps already created for this purpose often lack key elements, allowing invalid data to be entered and suggesting doses that might exceed the maximum safe dose. We describe the development of LoAD Calc, a mobile health (mHealth) app developed using a modified version of the Information Systems Research framework, which adds design thinking modes to the original framework. The app was enhanced through multiple iterations and developed with the aid of contextual observations and interviews, brainswarming sessions, prototyping, and continuous feedback. The design process led to the creation of two prototypes which underwent thorough testing by a sample of eight anesthesiologists. The final version of the app, LoAD Calc, was deployed on Apple and Android mobile test platforms and tested again by the same sample until deemed fit for release. Design thinking Development Dose calculation Drug safety Information systems research Local anesthetics Mobile apps Toxicity Dewey 617 63 Département d'anesthésiologie, pharmacologie, soins intensifs et urgences 229 false 538 Groupe Savoldelli Georges (simulation) 878 1280 Pharmaco-omiques et médecine de précision 1003 Healthcare 9 7 40bd3c13-7d57-4b29-a765-63fe6fbe687e Article (Published version) Public Article-scientifique-from-europePmc.pdf 21193543 application/pdf CC BY-4.0 openAccess Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences

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Development and Preliminary Validation of LoAD Calc, a Mobile App for Calculating the Maximum Safe Single Dose of Local Anesthetics	Healthcare			2021	129	61

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