In vitro evaluation of tooth-whitening potential of peroxide-free OTC dental bleaching agents

Article Article scientifique Article In vitro evaluation of tooth-whitening potential of peroxide-free OTC dental bleaching agents eng 2023-03-27 2023-03-27 author Grillon Marlène 748527 author Di Bella Enrico 948624 author Krejci Ivo 122923 Décanat et administration de la faculté de médecine (ADMED) author Ardu Stefano 0000-0003-1641-2168 506446 CUMD - Consultation de programmation (CPRO) 89 10.3390/dj11040089 2304-6767 https://www.mdpi.com/2304-6767/11/4/89 <p>Purpose: To evaluate and compare the tooth-whitening potential of five over-the-counter (OTC), peroxide-free dental bleaching methods as well as an experimental tooth-whitening solution containing 0.1% hydrogen peroxide complexed with doping agents with a gold standard (positive control) containing 16% carbamide peroxide. Material and Methods: Eighty permanent bovine incisor teeth were randomly allocated to eight different groups. Two teeth from each group were immerged into five staining solutions represented by coffee, tea, red wine, and curry mixed in warm oil or distilled water (control group) and stored at 37 °C for 28 days in an incubator. The teeth were then reallocated to the eight groups, resulting in ten samples per group, and each group was matched with a bleaching product. The bleaching procedures were executed following the manufacturer’s recommendations. The color of each sample was assessed over a white and black background using a quantitative numerical measurement approach with a calibrated spectrophotometer. Spectrophotometric measurements were performed after exposing the teeth to the bleaching agent for 60 min (T2), 100 min (T3), and 200 min (T4), and ΔE00 was calculated. Results: When analyzed over a white background, the mean ΔE00 values ranged from 2.14 (placebo) to 6.32 (Opalescence PF). When analyzed over a black background, the mean ΔE00 values ranged from 2.31 (placebo) to 5.78 (Opalescence PF). Statistically significant ΔE00 color changes over time for the eight groups and five staining solutions at T1 and T4 were assessed for both backgrounds using repeated ANOVA followed by Fisher’s LSD post hoc test (p-value < 0.01). Conclusions: All tested over-the-counter whitening kits except one exhibited positive color variation. However, the individual performance differed vastly from one brand to the other, and the overall performance was less effective compared to the conventional carbamide-peroxide-based positive control.</p> Dewey 617.6 205 Division de cariologie et d'endodontie 24P1 false 189 Groupe Krejci Ivo (médecine dentaire) 240 Dentistry journal 11 4 58e82f3d-42f4-4a04-b146-4a497f55a29c Article (Published version) Public Article-scientifique-from-crossref.pdf 1944526 application/pdf CC BY-4.0 1f59c8453c741352848f488df9da01dc27c14f237d30f5b9ee9cd2667a31db03 openAccess Faculté de médecine / Section de médecine dentaire / Département de médecine dentaire préventive et de premier recours / Division de cariologie et d'endodontie

Title	Published in	Year	Views	Downloads

In vitro evaluation of tooth-whitening potential of peroxide-free OTC dental bleaching agents	Dentistry journal	2023	95	523
Evaluation in vitro du potentiel d'agents de blanchiment dentaire OTC sans peroxyde		2021	541	5,579

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Grillon, Marlène