Early-stage cervical cancer: is surgery better than radiotherapy?

Article Article scientifique Revue de la littérature Early-stage cervical cancer: is surgery better than radiotherapy? eng 2010 author Undurraga Malinverno Manuela Stefania 758054 author Loubeyre Pierre 627417 author Dubuisson Jean-Bernard 135306 author Schneider Dominique Pierre 73772 author Petignat Patrick 586685 451-460 10.1586/era.09.192 20214525 1473-7140 Patients with early-stage cervical cancer may be treated appropriately with either radical surgery or radiation therapy. As most patients will be cured of their disease, side-effects of therapy and quality of life become of great importance. Individualization of treatment to reduce therapy-associated morbidity should be the main goal in cervical cancer management. Recent developments in surgical techniques, such as laparoscopy, nerve-sparing radical hysterectomy, sentinel lymph node biopsy, trachelectomy and 'less radical' hysterectomy, have contributed to reduce the morbidity of the surgical treatment. The use of postoperative radiotherapy or chemoradiation leads to more pronounced side effects than after either surgery or irradiation alone. Therefore, prognostic factors should be used to select patients for either surgery or radiotherapy alone to minimize the increased toxicities associated with the combination. The objectives of this review are to discuss the evidence supporting radical surgery, 'less radical' surgery and radiotherapy with regard to complication rate and quality of life. Combined Modality Therapy Female Humans Hysterectomy/methods Laparoscopy/methods Neoplasm Staging Patient Selection Quality of Life Sentinel Lymph Node Biopsy/methods Uterine Cervical Neoplasms/diagnosis/pathology/therapy Dewey 616.0757 Dewey 618 58 Département de pédiatrie, gynécologie et obstétrique 223 62 Département de radiologie et informatique médicale 227 false 590 Prévention du cancer du col utérin 933 Expert review of anticancer therapy 10 3 Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

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Early-stage cervical cancer: is surgery better than radiotherapy?	Expert review of anticancer therapy			2010	731	0

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Schneider, Dominique Pierre