Parallel nocturnal secretion of melatonin and testosterone in the plasma of normal men

Article Article scientifique Article Parallel nocturnal secretion of melatonin and testosterone in the plasma of normal men eng 1995 author Schulz Pierre 24731 author Chardon François Charles 70998 author Degli Agosti Robert 26498 author Schaad Nicolas 126846 author Rivest Robert William 21920 16-22 10.1111/j.1600-079X.1995.tb00166.x 0742-3098 Differences and similarities in the temporal organization of hormone secretion in plasma reflect the activity of CNS pacemakers. One aspect of this activity, the temporal synchronization of the secretion of different hormones is still poorly understood. We report the analysis of melatonin and testosterone plasma concentrations during two nights in 6 normal healthy young men. Blood was collected every 20 min between 2040 and 0640. Plasma testosterone concentrations increased by 1.5- to 2- fold during the second part of the night, and melatonin by 2.5-to 4-fold. In each subject. the individual temporal pattern of melatonin was quite stable over the two nights of sampling. while testosterone profiles showed fluctuations. There was a high degree of parallelism in these two hormones nocturnal secretion. These results, together with previous studies, suggest that melatonin might entrain the nocturnal secretion of testosterone Melatonin Testosterone Circadian rhythm Human Dewey 550 Dewey 615 Dewey 616.8 Dewey 616.89 41 Département F.-A. Forel des sciences de l'environnement et de l'eau 153 31 Section des sciences pharmaceutiques 17 53 Département de neurosciences fondamentales 21A 60 Département de psychiatrie 225 false Journal of pineal research 19 1 5a2563de-e02e-4a9e-b576-fdcbb5473591 Article (Published version) Restricted 00CC22t.pdf 899606 application/pdf restrictedAccess Faculté des sciences / Section des sciences de la Terre et de l'Environnement / Département F.-A. Forel des sciences de l'environnement et de l'eau Faculté des sciences / Section des sciences pharmaceutiques Faculté de médecine / Section de médecine fondamentale / Département de neurosciences fondamentales Faculté de médecine / Section de médecine clinique / Département de psychiatrie

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Parallel nocturnal secretion of melatonin and testosterone in the plasma of normal men	Journal of pineal research			1995	625	1

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Chardon, François Charles