Reporting of conflicts of interest and of sponsorship of guidelines in anaesthesiology. A cross-sectional study

Article Article scientifique Article Reporting of conflicts of interest and of sponsorship of guidelines in anaesthesiology. A cross-sectional study eng 2019 author Wyssa Damien 697631 author Tramer Martin 124140 author Elia Nadia 0000-0003-1787-9288 87569 e0212327 10.1371/journal.pone.0212327 30811517 1932-6203 Guideline recommendations may be biased due to conflicts of interest (COI) of panel members and sponsorship of the guideline. Potential impact of COI, and their management, should be transparently reported. We analysed 110 guidelines published in ten anaesthesia journals from 2007 to June 2018. We report on the number (%) that 1) published COI disclosures; 2) in a distinct paragraph; 3) described and explained the COI of panel members, and 4) of the Chairperson; 5) reported and described the presence or absence and potential impact of a sponsor of the guideline on the recommendations; and 6) reported how COI were managed. COI were published in 70/110 (64%) guidelines; in a distinct paragraph in 25/70 (36%). Panel members reported having no COI in 27/70 (39%) guidelines, disclosed COI without describing their potential impact in 41/70 (59%), and described their potential impact in 2/70 (3%). Chairpersons were identified in 50 guidelines, 32 of which published COI disclosures; 16/32 (50%) reported having no COI, 14/32 (44%) disclosed COI without describing their potential impact, 1/32 (3%) described their impact and 1/32 (3%) made no statement regarding COI. Presence or absence of a sponsor of the guideline was reported in 40 guidelines; 12/40 (30%) declared none, 24/40 (60%) reported sponsoring without explanation of the potential impact, and 4/40 (10%) described the potential influence of the sponsor on the guideline recommendations. Seventy-five guidelines reported COI of panel members and/or sponsorship of the guideline but only seven described how the COI had been managed. Disclosures of COI of panel members and of sponsors of guidelines have increased over the 12 year period, but remain insufficiently described and their potential influence on the guidelines' recommendations is poorly documented. Dewey 613 Dewey 617 63 Département d'anesthésiologie, pharmacologie, soins intensifs et urgences 229 66 Institut de santé globale 22A1 false 47 La médecine périopératoire et l'anesthésie 70 PLOS ONE 14 2 84b441a7-fb52-4d9c-8d11-c4498981b733 Article (Published version) Public Wyssa.pdf 1335223 application/pdf CC BY 26ac1e08-55f3-4ef0-baf2-f5df2e2c7b60 Supplemental data Public journal.pone.0212327.s001.pdf 138200 application/pdf CC BY 9c0edf65-b67d-457c-b634-ba96495664cb Supplemental data Public journal.pone.0212327.s002.pdf 59091 application/pdf CC BY b60d19bf-f26c-4683-9995-880e509c4a84 Supplemental data Public journal.pone.0212327.s003.pdf 123696 application/pdf CC BY openAccess Faculté de médecine / Section de médecine clinique / Département d'anesthésiologie, pharmacologie, soins intensifs et urgences Faculté de médecine / Section de médecine clinique / Département de santé et médecine communautaires / Institut de santé globale

Title	Published in	Year	Views	Downloads

Déclarations concernant les conflits d'intérêts des auteurs et les financements des directives en anesthésiologie		2021	651	320
Reporting of conflicts of interest and of sponsorship of guidelines in anaesthesiology. A cross-sectional study	PLOS ONE	2019	398	285

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Wyssa, Damien