Drug-Eluting Biodegradable Microspheres for Transarterial Chemoembolization

Diplôme Master Drug-Eluting Biodegradable Microspheres for Transarterial Chemoembolization eng 2014 author Loeliger François 659805 director Borchard Gerrit 0000-0001-6268-2586 635281 Chemoembolization is a well-recognized technique for intermediate to advanced cases of liver cancer. Hepatocellular carcinoma is the 3rd most common cause of cancer mortality and is the 5th most common form of cancer worldwide. It has many causes such as AFB1 intoxication, alcohol abuse, cirrhosis and hepatitis A and B infections. The need to produce biodegradable microspheres stems from the complications that arise from embolization with non-degradable ones, such as non-target embolization. To this, promising new drugs (sunitinib and sorafenib) have been marketed that increase the life expectancy of patients by 8 to 10 months. The aim of this paper was to produce biodegradable and biocompatible microspheres suitable for anticancer drug loading. Dewey 615 Travail personnel de recherche, Master en pharmacie 31 Section des sciences pharmaceutiques 17 false 879 Biopharmacie 81a35955-6e56-47fe-a3e1-c28da65bafa5 Master thesis Restricted TPR-UNIGE__[francois.loeliger-13.06.2014-11h00].pdf 2986126 application/pdf restrictedAccess Faculté des sciences / Section des sciences pharmaceutiques

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Drug-Eluting Biodegradable Microspheres for Transarterial Chemoembolization				2014	242	1

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Loeliger, François