UniPathway: a resource for the exploration and annotation of metabolic pathways

Article Article scientifique Article UniPathway: a resource for the exploration and annotation of metabolic pathways eng 2012 author Morgat Anne 639320 author Coissac Eric author Coudert Elisabeth 639263 author Axelsen Kristian Buhl 516917 author Keller Guillaume Bertrand 90403 author Bairoch Amos Marc 0000-0003-2826-6444 21964 author Bridge Alan James 561691 author Bougueleret Lydie 639268 author Xenarios Ioannis 767135 author Viari Alain D761-769 10.1093/nar/gkr1023 22102589 0305-1048 UniPathway (http://www.unipathway.org) is a fully manually curated resource for the representation and annotation of metabolic pathways. UniPathway provides explicit representations of enzyme-catalyzed and spontaneous chemical reactions, as well as a hierarchical representation of metabolic pathways. This hierarchy uses linear subpathways as the basic building block for the assembly of larger and more complex pathways, including species-specific pathway variants. All of the pathway data in UniPathway has been extensively cross-linked to existing pathway resources such as KEGG and MetaCyc, as well as sequence resources such as the UniProt KnowledgeBase (UniProtKB), for which UniPathway provides a controlled vocabulary for pathway annotation. We introduce here the basic concepts underlying the UniPathway resource, with the aim of allowing users to fully exploit the information provided by UniPathway. Databases, Factual Databases, Protein Enzymes/metabolism Lysine/biosynthesis Metabolic Networks and Pathways Molecular Sequence Annotation Dewey 576 136 Département de biologie structurale et bioinformatique 21E false 57 Calipho 80 Nucleic acids research 40 Database issue aa2e7b74-1e7d-4741-8cff-71ca0cfbe0e0 Article (Published version) Public pub_177_22102589.pdf 3029998 application/pdf openAccess Faculté de médecine / Section de médecine fondamentale / Département de biologie structurale et bioinformatique

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UniPathway: a resource for the exploration and annotation of metabolic pathways	Nucleic acids research			2012	620	813

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Morgat, Anne