Behavioural, haematological and histological studies on acute toxicity of bis(tri‐n‐butyltin oxide on Salmo gairdneri Richardson and Tilapia rendalli Boulenger

Article Article scientifique Article Behavioural, haematological and histological studies on acute toxicity of bis(tri‐n‐butyltin oxide on Salmo gairdneri Richardson and Tilapia rendalli Boulenger eng 2006-01-24 1977-06 author Chliamovitch Yves-Pierre 638722 author Kuhn C. 575-585 10.1111/j.1095-8649.1977.tb04090.x 0022-1112 https://onlinelibrary.wiley.com/doi/10.1111/j.1095-8649.1977.tb04090.x In acute toxicity tests based on the loss of positive rheotaxis, the relationship between exposure time and bis (tri‐ n ‐butyltin) oxide concentration was determined for Salmo gairdneri and Tilapia rendalli . This relationship may be represented by two superimposed rectangular hyperbolas (X‐d) (Y‐b)=c corresponding to two poisoning mechanisms. The 24‐h EC 50 is 30.8 μg/1 for trout and 53.2 μg/1 for T. rendalli . A histopathological study on S. gairdneri shows concentrations from 5.85 to 0.0117 mg TBTO/1 resulted in damage to the gill epithelium. At low concentrations a degeneration of the cornea and damage to the epithelial cells of bile ducts were also observed. Prior to a loss of positive rheotaxis and with concentrations from 0.023 to 1.17mg/l, the packed cell volume, the haemoglobin concentration and erythrocyte count increased. Determination of the mean cell volume showed swelling took place at 1.17 mg/1 but shrinkage was observed at 0.053 mg/1. These results indicate that TBTO interfered with the process of respiration. A ‘safe level’ (0.1 μg/1) is proposed for schistosomiasis control. Travaux du Département de biologie animale ; vol. 23, no 674 Dewey 590 44 Département de génétique et évolution 162 false Journal of fish biology 10 6 be902a72-c54d-42bc-afb0-27de360b9d4b Article (Published version) Restricted Chliamovitch_JFB_197710575.pdf 6690789 application/pdf 2a75d5f721e2c680ebd1c9f66d425e599f53653bd19278e8b33d8fb44aad5b04 restrictedAccess Faculté des sciences / Section de biologie / Département de génétique et évolution

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Behavioural, haematological and histological studies on acute toxicity of bis(tri‐n‐butyltin oxide on Salmo gairdneri Richardson and Tilapia rendalli Boulenger	Journal of fish biology			1977	1	0

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Chliamovitch, Yves-Pierre