Migration in patients with early psychosis : A 3-year prospective follow-up study

Article Article scientifique Article Migration in patients with early psychosis : A 3-year prospective follow-up study eng 2019-03-13 2019-05 author Golay Philippe Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Switzerland; Service of Community Psychiatry, Department of Psychiatry, Lausanne University Hospital (CHUV), Switzerland. Electronic address: Philippe.Golay@chuv.ch. 31349 author Baumann Philipp S Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Switzerland; Unit for Research in Schizophrenia, Center for Psychiatric Neuroscience, Lausanne University Hospital (CHUV), Switzerland. author Jaton Laure Psychiatric Liaison Service, Lausanne University Hospital (CHUV), Switzerland. 628867 author Restellini Romeo Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Switzerland; Unit for Research in Schizophrenia, Center for Psychiatric Neuroscience, Lausanne University Hospital (CHUV), Switzerland. 642332 author Solida Alessandra Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Switzerland. author Mebdouhi Nadir Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Switzerland. author Conus Philippe Service of General Psychiatry, Treatment and Early Intervention in Psychosis Program (TIPP-Lausanne), Lausanne University Hospital (CHUV), Switzerland. 108-114 10.1016/j.psychres.2019.03.021 30897392 0165-1781 https://www.sciencedirect.com/science/article/pii/S0165178119305025 Early psychosis programs treat high ratios of migrants, given they display higher rates of psychosis. Studies on this topic are limited and less is known about outcomes. The aim of this study was to compare the premorbid, baseline and outcome profile of patients according to migration (M) and migration in psychosocial adversity (MA) in order to explore if there were differences suggesting particular needs in terms of treatment. 257 early psychosis patients aged 18-35 years old were followed-up over 36 months. MA (29.6%) and M (17.9%) were compared to patients who were born in Switzerland (NM). At entry to the program, MA patients had poorer functional levels and higher symptom intensity. MA patients were more likely to report past exposure to trauma. While M patients have similar outcome compared to NM patients, MA patients were less likely to reach symptom remission, displayed lower functioning and were more likely to relapse. Results suggests that migration in adversity is a potential determinant of functional impairment in early psychosis. While patients who migrated in other contexts have a better outcome, patients who experienced migration in adversity have specific needs considering they are less integrated and more likely to have been exposed to trauma. Adolescent Adult Age of Onset Female Follow-Up Studies Human Migration Humans Male Prospective Studies Psychotic Disorders / epidemiology Psychotic Disorders / psychology Recurrence Switzerland / epidemiology Young Adult Swiss National Science Foundation Glutathion/redox dysregulation in early psychosis: towards a biomarker profile for early intervention 122419 CH Projects true Psychiatry research 275 baf2e3c7-63fc-4c3f-b954-4e41885a1db5 Article (Submitted version) Public Article_scientifique_from_unpaywall.pdf 2220252 application/pdf Restricted 2020-06-01 20601495316bc997caf966d698fa7d9d1fea372d00b1c2a56b3862161d40026a openAccess

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Migration in patients with early psychosis : A 3-year prospective follow-up study	Psychiatry research			2019	30	71

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