Bird breeder's disease: a rare diagnosis in young children

Article Article scientifique Rapport de cas Bird breeder's disease: a rare diagnosis in young children eng 2006 author Stauffer Mélanie 598605 author Pache Jean-Claude 513830 author Renevey François 63900 author Hanquinet Sylviane 133458 author Guinand Stéphane 113536 author Barazzone Constance 29124 55-61 10.1007/s00431-005-1762-4 16270199 0340-6199 Bird breeder's lung disease is the most common form of hypersensitivity pneumonitis and is a rare entity in young children. We report three cases of children under 7 years of age in whom this diagnosis was confirmed early in the course of the disease. Three children aged 4.4 to 6.5 years presented with dry cough lasting for more than 1 month, dyspnoea, variable loss of appetite, weight loss, fatigue, fever and mild signs of respiratory distress. Chest X-ray films and CT scans showed a bilateral micronodular infiltrate. All three patients had strongly suggestive bronchoalveolar lavage fluid findings with lymphocytosis; two had elevated cell counts and decreased CD4/CD8 ratios. Lung biopsy confirmed the diagnosis in all children. Contact with allergens was identified in all children: two had spent holidays close to a farm in the previous month and one was living next to a pigeon house. In all children, avian precipitins were positive. The symptoms rapidly resolved after allergen avoidance and treatment with oral prednisone. Corticoid treatment was given between 11 and 15 weeks. One child relapsed and required long-term low-dose corticotherapy for 1 year. Lung function tests were normal in all three patients, 3.9 to 5.7 years after diagnosis. Animals Bird Fancier's Lung/diagnosis/drug therapy Birds Child Child, Preschool Diagnosis, Differential Female Humans Male Radiography, Thoracic Tomography, X-Ray Computed Dewey 616.07 Dewey 616.0757 Dewey 618 Open Access - Licence nationale Springer 137 Département de pathologie et immunologie 21F 58 Département de pédiatrie, gynécologie et obstétrique 223 62 Département de radiologie et informatique médicale 227 false 148 Facteurs influençants le développement pulmonaire: étude translationnelle chez l'animal et l'homme 182 504 Radiologie neuro-diagnostique et neuro-interventionnelle en pédiatrie 842 European journal of pediatrics 165 1 990ae33d-867c-4140-a668-a4314d2b070c Article (Published version) Public 55-61.pdf 339661 application/pdf openAccess Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique Faculté de médecine / Section de médecine clinique / Département de radiologie et informatique médicale

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Bird breeder's disease: a rare diagnosis in young children	European journal of pediatrics			2006	593	325

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Stauffer, Mélanie